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Session: Inborn Errors of Immunity

Human Cytosolic Double-stranded RNA Sensors and SARS-COV-2 Susceptibility

Wednesday, June 19, 2024
1:00 PM – 1:25 PM PT
Location: Salons 3-6

    Speaker(s)

  • HS

    Helen C. Su, MD, PhD

    Chief, Human Immunological Diseases Section
    NIH/NIAID
    Bethesda, Maryland, United States

Disclosure(s):
Helen C. Su, MD, PhD: No relevant disclosure to display

Learning Objectives:

  • ... recognize that humans can exhibit a range of biochemically-defined inherited deficiencies in MDA5, RIG-I, and MAVS
  • ... understand how inherited defects in cytosolic double-stranded RNA sensors can cooperate for type I IFN responses to SARS-CoV-2
  • ... recognize that inherited defects in cytosolic double-stranded RNA sensors can contribute to COVID-19 clinical outcome