Immunoengineering and Therapeutics

Chair(s)

• 

  Jordan Pober, MD, PhD

  Yale University
  New Haven, Connecticut, United States

Presentations:

• 3:15 PM – 3:30 PM PT

  Tolerogenic IL-2 Containing Nanoparticles Induce CD4 and CD8 Regulatory T Cells and TGF-β Producing Regulatory NK Cells That Provide Essential Support for the Tregs Which Suppress Immune-mediated Disorders
  

  Presenting Author: David A. Horwitz, MD – General Nanotherapeutics, LLC
• 3:30 PM – 3:45 PM PT

  Rosnilimab, a PD-1 Agonist Antibody That Binds to a Membrane Proximal Epitope Leading to Optimized PD-1 Agonistic Signaling
  

  Presenting Author: Stephen Parmley, PhD – AnaptysBio
• 3:45 PM – 4:00 PM PT

  IL-10 Producing Tolerogenic Dendritic Cells Modulate B Cell Responses in vitro and in vivo
  

  Presenting Author: Silvia Gregori, PhD – San Raffaele Telethon institute for Gene Therapy
• 4:00 PM – 4:15 PM PT

  Precision Therapy for Lupus: Targeting Follicular Helper T Cells Using Chimeric Antigen Receptor Natural Killer Cells
  

  Presenting Author: Nora Lakes – Cincinnati Children's Hospital
• 4:15 PM – 4:30 PM PT

  T-cell Receptor Precision Editing of Regulatory T-cells for Celiac Disease
  

  Presenting Author: Raphael Porret – Lausanne University Hospital and University of Lausanne
• 4:30 PM – 4:45 PM PT

  Regeneration of a Sustained Antiviral Response in Transplant Recipients by Tacrolimus Resistant Antiviral T-cell Products
  

  Presenting Author: Niklas Wiese – Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin
• 4:45 PM – 5:00 PM PT

  Expanding Our Understanding of PDC-E2 T Cell Responses in PBC and Their Application for Eng Treg Therapy
  

  Presenting Author: Ritika Tewari, PhD – Benaroya Research Institute
• 5:00 PM – 5:15 PM PT

  Gene-edited Allogeneic Regulatory T Cells as 'Off-the-shelf' Immunomodulatory Therapy for Transplantation
  

  Presenting Author: Dimitrios L. Wagner, MD, PhD – Charité - Universitätsmedizin Berlin