- Monday, June 17, 2024
7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
8:00 AM – 4:30 PM PT
Systems Immunology Course (Separate Registration Required)
7:30 AM – 4:30 PM PT
Systems Immunology Course (Separate Registration Required)Chair: – Sanofi
Chair: – Roche
Emanuele de Rinaldis – Sanofi ### 2038981###Chair######Sanofi###Chair: – Sanofi
### @@@ Magnus Fontes, Ph.D. – Roche ### 751322###Chair######Roche###Chair: – Roche
### - Tuesday, June 18, 2024
7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
8:00 AM – 11:30 AM PT
Member Society Symposia
8:00 AM – 11:30 AM PT
Member Society Symposia
8:00 AM – 9:30 AM PT
Immunity at the Intestinal Barrier
8:00 AM – 11:30 AM PT
Crosstalk Between Stress and Immunity
8:00 AM – 11:30 AM PT
Investigating Common Mechanisms of Autoimmunity
8:00 AM – 11:30 AM PT
New Frontiers in B Cell/antibody Responses
10:00 AM – 11:30 AM PT
Immune Responses at the Barrier Sites Through the Lenses of New Nomenclature of Allergy and Clinical Immunology
8:00 AM – 12:00 PM PT
Big Data in Immunology Workshop (Separate Registration Required)
7:30 AM – 12:00 PM PT
Big Data in Immunology Workshop (Separate Registration Required)Chair: – University of California, San Francisco
Sanchita Bhattacharya, PhD – University of California, San Francisco ### 365757###Chair###Bioinformatics Project Leader###University of California, San Francisco###Chair: – University of California, San Francisco
### 8:30 AM – 5:30 PM PT
Basic Immunology in Medicine Course (Separate Registration Required)
8:00 AM – 5:30 PM PT
Basic Immunology in Medicine Course (Separate Registration Required)Chair: – University of California, San Francisco
Chair: – University of California, San Francisco
Abul Abbas, MD – University of California, San Francisco ### 751324###Chair######University of California, San Francisco###Chair: – University of California, San Francisco
### @@@ Mark Anderson, MD, PhD – University of California, San Francisco ### 435351###Chair###Professor and Director, UCSF Diabetes Center###University of California, San Francisco###Chair: – University of California, San Francisco
### 11:30 AM – 1:00 PM PT
Sponsor Lunch
11:30 AM – 1:00 PM PT
Sponsor Lunch
1:30 PM – 5:00 PM PT
Member Society Symposia
1:30 PM – 5:00 PM PT
Member Society Symposia
1:30 PM – 3:00 PM PT
Advances in Mast Cell Research
1:30 PM – 3:00 PM PT
Interaction Between Environmental Factors and Immune System in Immune-mediated Diseases
1:30 PM – 5:00 PM PT
APS1 and Immune Tolerance: From Basic Biology to Clinical Translation
1:30 PM – 5:00 PM PT
Expanding and Unlocking the Tools of Immunotherapy to Improve Understanding and Treatment for Cancer, Autoimmune Disease and Transplantation
1:30 PM – 5:00 PM PT
Latin-American Immunologists Symposium
3:30 PM – 5:00 PM PT
IL-9: From Birth to Breath
3:30 PM – 5:00 PM PT
The Environment, Air Pollution, Microbiome and Allergy and Vaccines in Transplant Patients
5:30 PM – 6:15 PM PT
Keynote Session
5:30 PM – 6:15 PM PT
Opening Keynote Address: XenotransplantationLocation: Salon 8Speaker: – NYU Langone Health
Chair: – Columbia University
Robert A. Montgomery, MD, D.Phil, FACS (he/him/his) – NYU Langone Health ### 2203666###Speaker###H. Leon Pachter Chair & Professor of Surgery###NYU Langone Health###Speaker: – NYU Langone Health
### he/him/his @@@ Megan Sykes, MD (she/her/hers) – Columbia University ### 366755###Chair###Michael J. Friedlander Professor of Medicine and Professor of Microbiology & Immunology and Surgical Sciences (in Surgery), Columbia University
Director, Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons
Director of Research, Transplant Initiative,
Director, Bone Marrow Transplantation Research, Division of Hematology/Oncology
Columbia University Medical Center
###Columbia University###Chair: – Columbia University
### she/her/hers6:15 PM – 7:30 PM PT
Opening Reception: Exhibits & Poster Presentations
6:15 PM – 7:30 PM PT
Opening Reception: Exhibits & Poster PresentationsLocation: Salon 9
- Wednesday, June 19, 2024
7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
Location: Salon 9
7:30 AM – 7:30 PM PT
Exhibition & Poster Hall Open (authors optional)
7:30 AM – 7:30 PM PT
Exhibition & Poster Hall Open (authors Optional)
Location: Salon 9
8:00 AM – 9:30 AM PT
Novel Pathways and Approaches in Allergic DiseaseChair: – Northwestern University
8:00 AM – 9:30 AM PT
Novel Pathways and Approaches in Allergic DiseaseChair: – Northwestern University
Stephanie C. Eisenbarth, MD, PhD – Northwestern University ### 2311253###Chair######Northwestern University###Chair: – Northwestern University
### 8:00 AM – 8:30 AM PT
Repurposing Approved Bruton’s Tyrosine Kinase Inhibitors for the Prevention of AnaphylaxisSpeaker: – Johns Hopkins University School of Medicine
Melanie C. Dispenza, MD, PhD (she/her/hers) – Johns Hopkins University School of Medicine ### 2203654###Speaker###Assistant Professor of Medicine###Johns Hopkins University School of Medicine###Speaker: – Johns Hopkins University School of Medicine
### she/her/hers8:30 AM – 9:00 AM PT
Computational Engineering of Major Allergens to Reduce Allergenicity and Maintain Immunogenicity Enables Safe and Effective Immunotherapy for Food Allergy
Yanay Ofran, PhD – Ukko, Inc. ### 1541307###Speaker###Founder###Ukko, Inc.###Speaker: – Ukko, Inc.
### 9:00 AM – 9:30 AM PT
Regulation of Allergic Responses to Food by Commensal Bacterial Products and MetabolitesSpeaker: – University of Chicago
Cathryn Nagler, PhD (she/her/hers) – University of Chicago ### 308427###Speaker###Professor###University of Chicago###Speaker: – University of Chicago
### she/her/hers9:30 AM – 10:00 AM PT
Coffee Break
9:30 AM – 10:00 AM PT
Coffee Break
10:00 AM – 11:30 AM PT
Precision Therapeutics in Mucosal Disorders
10:00 AM – 11:30 AM PT
Precision Therapeutics in Mucosal Disorders
10:00 AM – 10:30 AM PT
Microbial Host Defense and Influence in CancerSpeaker: – University of Texas MD Anderson Cancer Center
Florencia McAllister, MD – University of Texas MD Anderson Cancer Center ### 2203663###Speaker###Associate Professor###University of Texas MD Anderson Cancer Center###Speaker: – University of Texas MD Anderson Cancer Center
### 10:30 AM – 11:00 AM PT
Precision Therapeutics in Inflammatory Bowel Disease--defining Disease Subtypes & Therapeutic GoalsSpeaker: – Icahn School of Medicine at Mount Sinai
Judy H. Cho, MD (she/her/hers) – Icahn School of Medicine at Mount Sinai ### 520548###Speaker###Professor###Icahn School of Medicine at Mount Sinai###Speaker: – Icahn School of Medicine at Mount Sinai
### she/her/hers11:00 AM – 11:30 AM PT
Microbiome Therapies in Food AllergySpeaker: – Boston Children's Hospital
Rima Rachid, MD (she/her/hers) – Boston Children's Hospital ### 2232700###Speaker###Co-Director, Food Allergy Program###Boston Children's Hospital###Speaker: – Boston Children's Hospital
### she/her/hers11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:30 AM – 1:00 PM PT
2024 Lupus Insight Prize Award Ceremony and Luncheon
11:45 AM – 1:00 PM PT
Industry Tutorial: Optimized immunophenotyping with high dimensional spectral flow cytometry panels
Zayda Piedra, PhD ### 2317893###Speaker#########Speaker:
### 1:00 PM – 2:45 PM PT
Immune Responses to GT/TherapeuticsChair: – University of British Columbia
1:00 PM – 2:45 PM PT
Immune Responses to GT/TherapeuticsChair: – University of British Columbia
Megan K. Levings, PhD (she/her/hers) – University of British Columbia ### 365464###Chair###Professor###University of British Columbia###Chair: – University of British Columbia
### she/her/hers1:00 PM – 1:25 PM PT
Human Immune Responses to Viral Gene Therapy VectorsSpeaker: – Nava Therapeutics
Federico Mingozzi, PhD (he/him/his) – Nava Therapeutics ### 2203664###Speaker###CEO###Nava Therapeutics###Speaker: – Nava Therapeutics
### he/him/his1:25 PM – 1:40 PM PT
Pantreg: A Cell-therapy, System-biology - Based Approach for Therapy of AutoimmunityPresenting Author: – Translational Immunology Institute, SingHealth
Oral
Salvatore Albani, MD, PhD – Translational Immunology Institute, SingHealth ### 365688###Presenting Author###Director###Translational Immunology Institute, SingHealth###Presenting Author: – Translational Immunology Institute, SingHealth
### 1:40 PM – 2:05 PM PT
Preclinical and Clinical Development of Tolerogenic Immtor Nanoparticles to Mitigate Immunogenicity of Biologic and Gene TherapiesSpeaker: – Selecta Biosciences
Kei Kishimoto, PhD (he/him/his) – Selecta Biosciences ### 366581###Speaker###former CSO###Selecta Biosciences###Speaker: – Selecta Biosciences
### he/him/his2:05 PM – 2:20 PM PT
Car-ts Are Getting Viral! a New Method for Allogenic CAR-T Cell Therapy DevelopmentPresenting Author: – IDIBAPS
Oral
Mario Vazquez – IDIBAPS ### 2288177###Presenting Author######IDIBAPS###Presenting Author: – IDIBAPS
### 2:20 PM – 2:45 PM PT
Derivation of Clinically Relevant T-lymphocytes from Human IpscSpeaker: – Boston University School of Medicine
Gustavo Mostoslavsky, MD, PhD (he/him/his) – Boston University School of Medicine ### 1139704###Speaker###Professor of Medicine###Boston University School of Medicine###Speaker: – Boston University School of Medicine
### he/him/his1:00 PM – 2:45 PM PT
Inborn Errors of ImmunityChair: – University of Colorado
1:00 PM – 2:45 PM PT
Inborn Errors of ImmunityChair: – University of Colorado
Elena WY Hsieh, MD – University of Colorado ### 1608904###Chair###Associate Professor###University of Colorado###Chair: – University of Colorado
### 1:00 PM – 1:25 PM PT
Human Cytosolic Double-stranded RNA Sensors and SARS-COV-2 Susceptibility
Helen C. Su, MD, PhD – NIH/NIAID ### 741312###Speaker###Chief, Human Immunological Diseases Section###NIH/NIAID###Speaker: – NIH/NIAID
### 1:25 PM – 1:40 PM PT
STAT1 Gain-of-function Leads to Dysfunctional T Regulatory CellsPresenting Author: – University of California San Francisco
Oral
Martin Thelin, MD, PhD – University of California San Francisco ### 2288176###Presenting Author######University of California San Francisco###Presenting Author: – University of California San Francisco
### 1:40 PM – 2:05 PM PT
Inborn Errors of Immunity - Gene Therapy for Wiskott-aldrich SyndromeSpeaker: – Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute
Sung-Yun Pai, MD (she/her/hers) – Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute ### 2203668###Speaker###Chief and Senior Investigator###Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute###Speaker: – Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute
### she/her/hers2:05 PM – 2:20 PM PT
Human OTULIN Mutations Can Cause Distinct Inflammatory Disease Phenotypes Depending on the Protein Domain That Is MutatedPresenting Author: – Vanderbilt University Medical Center
Oral
Hwi Gil – Vanderbilt University Medical Center ### 2288170###Presenting Author######Vanderbilt University Medical Center###Presenting Author: – Vanderbilt University Medical Center
### 2:20 PM – 2:45 PM PT
Genetic Architecture of Inborn Errors of ImmunitySpeaker: – Columbia University
Dusan Bogunovic, PhD – Columbia University ### 651467###Speaker###Professor###Columbia University###Speaker: – Columbia University
### 1:00 PM – 2:45 PM PT
Systems Immunology & AI Chair: – Brigham and Women's Hospital
1:00 PM – 2:45 PM PT
Systems Immunology & AIChair: – Brigham and Women's Hospital
Deepak A. Rao, MD, PhD – Brigham and Women's Hospital ### 651483###Chair###Assistant Professor of Medicine###Brigham and Women's Hospital###Chair: – Brigham and Women's Hospital
### 1:00 PM – 1:25 PM PT
Conserved Spatial Programs of Immune Regulation in Human Health and DiseaseSpeaker: – Stanford University
Michael Angelo, MD, PhD – Stanford University ### 985973###Speaker###Associate Professor###Stanford University###Speaker: – Stanford University
### 1:25 PM – 1:40 PM PT
Epigenetic Signature and Key Transcriptional Regulators of Human Antigen-inducible Regulatory T CellsPresenting Author: – Stanford University School of Medicine
Oral
Alma-Martina Cepika, MD, PhD – Stanford University School of Medicine ### 1310188###Presenting Author###Instructor###Stanford University School of Medicine###Presenting Author: – Stanford University School of Medicine
### 1:40 PM – 2:05 PM PT
Single-cell to Tissue-scale Memory in the NoseSpeaker: – Boston Children's Hospital
Jose Ordovas-Montanes, PhD – Boston Children's Hospital ### 987320###Speaker###Assistant Professor###Boston Children's Hospital###Speaker: – Boston Children's Hospital
### 2:05 PM – 2:20 PM PT
Unsupervised and Supervised Machine Learning Promotes Translational Research of Autoimmune DiseasesPresenting Author: – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre
Oral
Martin Wasser, PhD – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre ### 1945837###Presenting Author###Principal Biostatistician###Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre###Presenting Author: – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre
### 2:20 PM – 2:45 PM PT
T Cell Immunity in the Acute Myeloid Leukemia Bone MarrowSpeaker: – Memorial Sloan Kettering Cancer Center
Susan De Wolf, MD – Memorial Sloan Kettering Cancer Center ### 2203653###Speaker###Assistant Attending ###Memorial Sloan Kettering Cancer Center###Speaker: – Memorial Sloan Kettering Cancer Center
### 2:45 PM – 3:15 PM PT
Coffee Break
2:45 PM – 3:15 PM PT
Coffee Break
3:15 PM – 5:15 PM PT
Autoimmunity and TransplantationChair: – University of Rouen Normandy
3:15 PM – 5:15 PM PT
Autoimmunity and TransplantationChair: – University of Rouen Normandy
Olivier Boyer, MD, PhD – University of Rouen Normandy ### 986295###Chair######University of Rouen Normandy###Chair: – University of Rouen Normandy
### 3:15 PM – 3:30 PM PT
The Role of Recipient γδ T Cells in Graft Rejection After Human Intestinal TransplantationPresenting Author: – Columbia University
Stem Cell and Organ Transplantation
Jianing Fu, PhD – Columbia University ### 987248###Presenting Author###Associate Research Scientist###Columbia University###Presenting Author: – Columbia University
### 3:30 PM – 3:45 PM PT
Inferring Disease Mechanisms in Lupus Nephritis: lessons from the Accelerating Medicines Partnership (AMP) in SLE ConsortiumPresenting Author: – The Feinstein Institutes for Medical Research
Autoimmune Diseases
Arnon Arazi, PhD – The Feinstein Institutes for Medical Research ### 1945809###Presenting Author###Assistant Professor###The Feinstein Institutes for Medical Research###Presenting Author: – The Feinstein Institutes for Medical Research
### 3:45 PM – 4:00 PM PT
High Dimensional, Single Cell Analysis of Epstein Barr Virus (EBV)-Specific T Cells from Pediatric Transplant Recipients with EBV Dnaemia or Controlled InfectionPresenting Author: – Stanford University School of Medicine
Stem Cell and Organ Transplantation
Edward A. Vizcarra, Ph.D. – Stanford University School of Medicine ### 2300053###Presenting Author###Postdoctoral Fellow###Stanford University School of Medicine###Presenting Author: – Stanford University School of Medicine
### 4:00 PM – 4:15 PM PT
Immunophenotypic Profiling Reveals Novel T Cell Subset Associated with “tolerance” in Pediatric Transplant RecipientsPresenting Author: – Stanford University
Stem Cell and Organ Transplantation
Wenming Zhang, PhD – Stanford University ### 741090###Presenting Author######Stanford University###Presenting Author: – Stanford University
### 4:15 PM – 4:30 PM PT
Pharmacodynamic Demonstration of Immunological Tolerance Induced by KAN-101, a Novel Liver-targeted Therapy for Celiac DiseasePresenting Author: – Anokion
Autoimmune Diseases
Kristie M. Grebe, PhD – Anokion ### 2300057###Presenting Author###Chief Scientific Officer###Anokion###Presenting Author: – Anokion
### 4:30 PM – 4:45 PM PT
Single Cell Analysis of CD8 T-cells Reveals Autoantigen Specific Signatures of Teplizumab Treatment in at Risk Subjects from the trialnet-10 StudyPresenting Author: – Benaroya Research Institute
Autoimmune Diseases
Hai T. Nguyen, PhD – Benaroya Research Institute ### 519951###Presenting Author###Research Scientist###Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 4:45 PM – 5:00 PM PT
BiTEing Multi-drug Resistant Rheumatoid Arthritis with CD19-T Cell EngagersPresenting Author: – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen
Autoimmune Diseases
Ricardo Grieshaber-Bouyer, Prof. Dr. med. – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen ### 2300065###Presenting Author######Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen###Presenting Author: – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen
### 5:00 PM – 5:15 PM PT
Donor-specific T Cell Activation and Expansion Following a Pig-to-human Decedent Kidney TransplantPresenting Author: – Columbia University
Stem Cell and Organ Transplantation
Farshid Fathi, PhD – Columbia University ### 2039349###Presenting Author###Post Doc###Columbia University###Presenting Author: – Columbia University
### 3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 1
3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 1Chair: – Stanford University
Holden T. Maecker, PhD – Stanford University ### 387249###Chair###Professor (Research)###Stanford University###Chair: – Stanford University
### 3:15 PM – 5:15 PM PT
ImmunogeneticsChair: – University of California, Los Angeles
3:15 PM – 5:15 PM PT
ImmunogeneticsChair: – University of California, Los Angeles
Elaine F. Reed, PhD – University of California, Los Angeles ### 366880###Chair###Professor###University of California, Los Angeles###Chair: – University of California, Los Angeles
### 3:15 PM – 3:30 PM PT
Local Intestinal Eosinophilic Activation Triggered by Defective Epithelial TGF-β Signaling Underlies IPO8 DeficiencyPresenting Author: – Institut Imagine
Allergy
Marianna Parlato, PhD – Institut Imagine ### 2300050###Presenting Author######Institut Imagine###Presenting Author: – Institut Imagine
### 3:30 PM – 3:45 PM PT
CLEC16A-driven Mitophagy Limits Astrocyte Proinflammatory ActivitiesPresenting Author: – Osaka University
Neuroimmunology
Atsushi Kadowaki, MD, PhD – Osaka University ### 2300051###Presenting Author######Osaka University###Presenting Author: – Osaka University
### 3:45 PM – 4:00 PM PT
Single-cell RNA-seq Analysis of PBMCs of Three Cameroonian Populations Reveals Differences in Cell Type Distribution as Well as Differentially Expressed GenesPresenting Author: – University of Pennsylvania
Systems Immunology
Etiena Basner Tschakarjan, MD PhD – University of Pennsylvania ### 2300056###Presenting Author######University of Pennsylvania###Presenting Author: – University of Pennsylvania
### 4:00 PM – 4:15 PM PT
Intra-clonal Diversity of Donor Specific B Cell Igh Is Associated with Pathogenic Allo-immunityPresenting Author: – University of Michigan
Stem Cell and Organ Transplantation
Marilia Cascalho, MD PhD – University of Michigan ### 1996180###Presenting Author###Professor###University of Michigan###Presenting Author: – University of Michigan
### 4:15 PM – 4:30 PM PT
Oral Pathobionts Promote CRC Development by Alteration of the Host Epigenome and Immunomic MicroenvironmentPresenting Author: – Mayo Clinic, Arizona, Scottsdale
Mucosal Immunology
Shirin Eyvazi Khasraghi, MSc/ PhD – Mayo Clinic, Arizona, Scottsdale ### 2300052###Presenting Author###Postdoctoral Fellow###Mayo Clinic, Arizona, Scottsdale###Presenting Author: – Mayo Clinic, Arizona, Scottsdale
### 4:30 PM – 4:45 PM PT
Mechanistic Investigation of Human DPP9 DeficiencyPresenting Author: – Yale University
Immunogenetics
Tianli Xiao, Ph.D – Yale University ### 2300063###Presenting Author###Postdoctoral fellow###Yale University###Presenting Author: – Yale University
### 4:45 PM – 5:00 PM PT
Abnormal STAT3 Signaling in Fibroblasts Promotes Staphylococcal Growth and Abnormal Tissue Response to InfectionPresenting Author: – Columbia University
Infectious Diseases
Miao Chen, PhD – Columbia University ### 2300055###Presenting Author###Postdoc Research Scientist###Columbia University###Presenting Author: – Columbia University
### 5:00 PM – 5:15 PM PT
Genome-wide Autoimmune Genetic Variant Perturbations Connect Genetic Risk to Primary T Cell Expression and FunctionPresenting Author: – Benaroya Research Institute
Immunogenetics
John Ray, PhD – Benaroya Research Institute ### 534435###Presenting Author###Assistant Member###Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 3:15 PM – 5:15 PM PT
Late-Breaking Abstracts (Announced in May)
3:15 PM – 5:15 PM PT
Late-Breaking Abstracts (Announced in May)
5:30 PM – 6:15 PM PT
Keynote Session - Robert B. Nussenblatt Presidential Lecture
5:30 PM – 6:15 PM PT
Keynote Address - Robert. B. Nussenblatt Presidential Lecture: Human Auto-, Allo- and Xeno-reactive T Cell Repertoire Dynamics and TranscriptomicsSpeaker: – Columbia University
Chair: – Nantes University
Megan Sykes, MD (she/her/hers) – Columbia University ### 366755###Speaker###Michael J. Friedlander Professor of Medicine and Professor of Microbiology & Immunology and Surgical Sciences (in Surgery), Columbia University
Director, Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons
Director of Research, Transplant Initiative,
Director, Bone Marrow Transplantation Research, Division of Hematology/Oncology
Columbia University Medical Center
###Columbia University###Speaker: – Columbia University
### she/her/hers @@@ Ignacio Anegon – Nantes University ### 2040761###Chair######Nantes University###Chair: – Nantes University
### 6:15 PM – 7:30 PM PT
Exhibits & Poster Presentations Reception
6:15 PM – 7:30 PM PT
Exhibits & Poster Presentations Reception
Location: Salon 9
7:30 PM – 8:30 PM PT
FOCIS Member Reception (FOCIS members only)
7:30 PM – 8:30 PM PT
FOCIS Member Reception (FOCIS Members Only)
Location: SoMa
- Thursday, June 20, 2024
7:00 AM – 8:00 AM PT
Working Towards Inclusion and Belonging at FOCIS and Beyond
7:00 AM – 8:00 AM PT
Working Towards Inclusion and Belonging at FOCIS and BeyondChair: – Weill Cornell Medicine
Speaker: – Independent Consultant
Monica L. Guzman, PhD (she/her/hers) – Weill Cornell Medicine ### 751352###Chair###Associate Professor of Pharmacology in Medicine###Weill Cornell Medicine###Chair: – Weill Cornell Medicine
### she/her/hers @@@ Yanet Valdez Tejeira, MSc., PhD (she/her/hers) – Independent Consultant ### 1695650###Speaker###Mucosal Immunologist###Independent Consultant###Speaker: – Independent Consultant
### she/her/hers7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
Location: Salon 9
7:30 AM – 7:45 PM PT
Exhibition & Poster Hall Open (authors optional)
7:30 AM – 7:45 PM PT
Exhibition & Poster Hall Open (authors Optional)
Location: Salon 9
8:00 AM – 9:30 AM PT
NeuroimmunologyChair: – Inserm U1234, FCE PAn'THER
8:00 AM – 9:30 AM PT
NeuroimmunologyChair: – Inserm U1234, FCE PAn'THER
Catalina Abad, PhD – Inserm U1234, FCE PAn'THER ### 741068###Chair###Research engineer###Inserm U1234, FCE PAn'THER###Chair: – Inserm U1234, FCE PAn'THER
### 8:00 AM – 8:30 AM PT
Interrogating Antigen-specific T Cell Responses in Neurodegenerative DisordersSpeaker: – Columbia University
Wassim Elyaman, PhD – Columbia University ### 738506###Speaker###Assistant Professor###Columbia University###Speaker: – Columbia University
### 8:30 AM – 9:00 AM PT
Autologous Cell Therapy for Parkinson’s Disease: From Bench to Bed and from Bed to BenchSpeaker: – McLean Hospital/Harvard Medical School
Kwang-Soo Kim, PhD – McLean Hospital/Harvard Medical School ### 2203662###Speaker###Professor and Director###McLean Hospital/Harvard Medical School###Speaker: – McLean Hospital/Harvard Medical School
### 9:00 AM – 9:30 AM PT
The Role of the Immune System in A-synucleinopathiesSpeaker: – University of Alabama at Birmingham
Ashley S. Harms, PhD (she/her/hers) – University of Alabama at Birmingham ### 2203659###Speaker###Associate Professor###University of Alabama at Birmingham###Speaker: – University of Alabama at Birmingham
### she/her/hers9:30 AM – 10:00 AM PT
Coffee Break
9:30 AM – 10:00 AM PT
Coffee Break
10:00 AM – 11:30 AM PT
Immunology in Reproductive HealthChair: – National University of Cordoba, CIBICI-CONICET
10:00 AM – 11:30 AM PT
Immunology in Reproductive HealthChair: – National University of Cordoba, CIBICI-CONICET
Rubén D. Motrich – National University of Cordoba, CIBICI-CONICET ### 2310091###Chair######National University of Cordoba, CIBICI-CONICET###Chair: – National University of Cordoba, CIBICI-CONICET
### 10:00 AM – 10:30 AM PT
Immunology Learned from Mothers and BabiesSpeaker: – University of Cincinnati
Sing Sing Way, MD, PhD – University of Cincinnati ### 2203674###Speaker######University of Cincinnati###Speaker: – University of Cincinnati
### 10:30 AM – 11:00 AM PT
Immune Communication Between Mother and Fetus During Pregnancy and Its Long Term ConsequencesSpeaker: – Helmholtz Centre for Environmental Research-UFZ
Ana C. Zenclussen, PhD (she/her/hers) – Helmholtz Centre for Environmental Research-UFZ ### 2203675###Speaker###Head of the Department Environmental Immunology###Helmholtz Centre for Environmental Research-UFZ###Speaker: – Helmholtz Centre for Environmental Research-UFZ
### she/her/hers11:00 AM – 11:30 AM PT
The Unraveling of Microbial-immune Interactions in the Reproductive TrackSpeaker: – Icahn School of Medicine at Mount Sinai
Michal Elovitz, MD (she/her/hers) – Icahn School of Medicine at Mount Sinai ### 2203656###Speaker###Dean, Women's Health###Icahn School of Medicine at Mount Sinai###Speaker: – Icahn School of Medicine at Mount Sinai
### she/her/hers11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:30 AM – 1:00 PM PT
WICI/WIT SessionChair: – University of California, Los Angeles
Speaker: – Stanford University
Elaine F. Reed, PhD – University of California, Los Angeles ### 366880###Chair###Professor###University of California, Los Angeles###Chair: – University of California, Los Angeles
### @@@ Arghavan Salles, MD, PhD (she/her/hers) – Stanford University ### 2300631###Speaker###Clinical Associate Professor (Gastroenterology and Hepatology)###Stanford University###Speaker: – Stanford University
### she/her/hers11:45 AM – 1:00 PM PT
Industry Tutorial: Alamar Biosciences
1:00 PM – 2:45 PM PT
Cellular & Stem Cell TherapeuticsChair: – Nantes University
1:00 PM – 2:45 PM PT
Cellular & Stem Cell TherapeuticsChair: – Nantes University
Ignacio Anegon – Nantes University ### 2040761###Chair######Nantes University###Chair: – Nantes University
### 1:00 PM – 1:25 PM PT
Protecting Transplanted Cells from Immune Rejection Is the Key to Unlocking the Potential of Regenerative MedicineSpeaker: – Sana Biotechnology
Sonja Schrepfer, MD, PhD (she/her/hers) – Sana Biotechnology ### 2203671###Speaker###SVP, Head of Hypoimmune Platform###Sana Biotechnology###Speaker: – Sana Biotechnology
### she/her/hers1:25 PM – 1:40 PM PT
type-2 Functionality in Sustaining CAR T Cell Longevity Linked to 8-year Leukemia RemissionPresenting Author: – Yale University
Oral
Zhiliang Bai, PhD – Yale University ### 2288181###Presenting Author###Postdoc Associate###Yale University###Presenting Author: – Yale University
### 1:40 PM – 2:05 PM PT
TCR Engineered Tregs for Autoimmune DiseasesSpeaker: – Abata Therapeutics
Devan Moodley, PhD (he/him/his) – Abata Therapeutics ### 2203667###Speaker###Senior Director###Abata Therapeutics###Speaker: – Abata Therapeutics
### he/him/his2:05 PM – 2:20 PM PT
TCR Avidity Influences Signaling and Function of Engineered TregPresenting Author: – Benaroya Research Institute
Oral
Soo Jung Yang, Ph.D. – Benaroya Research Institute ### 987461###Presenting Author######Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 2:20 PM – 2:45 PM PT
Engineering Regulatory T Cells for ToleranceSpeaker: – University of British Columbia
Megan K. Levings, PhD (she/her/hers) – University of British Columbia ### 365464###Speaker###Professor###University of British Columbia###Speaker: – University of British Columbia
### she/her/hers1:00 PM – 2:45 PM PT
Host Defense and Vaccinology
1:00 PM – 2:45 PM PT
Host Defense and Vaccinology
Galit Alter, PhD (she/her/hers) – Moderna ### 2203648###Chair###Vice President, Immunology Research###Moderna###Chair: – Moderna
### she/her/hers1:00 PM – 1:25 PM PT
Systems Biological Analysis of the Mechanisms and Predictors of the Durability of Vaccine ResponsesSpeaker: – Stanford University
Bali Pulendran, PhD – Stanford University ### 1196163###Speaker###Professor###Stanford University###Speaker: – Stanford University
### 1:25 PM – 1:40 PM PT
sars-cov-2 Vaccination Provides Boosted Mucosal Protection in Previously Infected Young ChildrenPresenting Author: – Boston Children's Hospital
Oral
Ying Tang, Ph.D. – Boston Children's Hospital ### 1139949###Presenting Author###Research Fellow###Boston Children's Hospital###Presenting Author: – Boston Children's Hospital
### 1:40 PM – 2:05 PM PT
Human Antibody Response to sars-cov-1 and sars-cov-2Speaker: – Tsinghua University
Linqi Zhang, PhD (he/him/his) – Tsinghua University ### 2203676###Speaker###Professor###Tsinghua University###Speaker: – Tsinghua University
### he/him/his2:05 PM – 2:20 PM PT
Sequential Phases of Follicular Helper T Cell Development and Their Impact on Humoral Immune Responses to VaccinationPresenting Author: – Fondazione IRCCS Ca' Granda Ospedale Policlinico, Brigham and Women’s Hospital
Oral
Manuel A. Podestà – Fondazione IRCCS Ca' Granda Ospedale Policlinico, Brigham and Women’s Hospital ### 2288174###Presenting Author###Postdoctoral Research Fellow###Fondazione IRCCS Ca' Granda Ospedale Policlinico, Brigham and Women’s Hospital###Presenting Author: – Fondazione IRCCS Ca' Granda Ospedale Policlinico, Brigham and Women’s Hospital
### 2:20 PM – 2:45 PM PT
Dissecting Humoral Vaccine Correlates of Protection Across Respiratory Pathogens
Galit Alter, PhD (she/her/hers) – Moderna ### 2203648###Speaker###Vice President, Immunology Research###Moderna###Speaker: – Moderna
### she/her/hers1:00 PM – 2:45 PM PT
Organoid Modeling & TherapeuticsChair: – Charité - Universitätsmedizin Berlin
1:00 PM – 2:45 PM PT
Organoid Modeling & TherapeuticsChair: – Charité - Universitätsmedizin Berlin
Dimitrios L. Wagner, MD, PhD – Charité - Universitätsmedizin Berlin ### 740535###Chair###Research Associate###Charité - Universitätsmedizin Berlin###Chair: – Charité - Universitätsmedizin Berlin
### 1:00 PM – 1:25 PM PT
Tonsil Organoids to Investigate Human Adaptive ImmunitySpeaker: – University of California Irvine
Lisa Wagar, PhD (she/her/hers) – University of California Irvine ### 2203673###Speaker###Assistant Professor###University of California Irvine###Speaker: – University of California Irvine
### she/her/hers1:25 PM – 1:40 PM PT
Tissue-specific Sex Differences in Pediatric and Adult Immune Cell Composition and FunctionPresenting Author: – University of California Irvine
Oral
Mahina Tabassum Mitul, MSc. – University of California Irvine ### 2288180###Presenting Author###Graduate Student Researcher###University of California Irvine###Presenting Author: – University of California Irvine
### 1:40 PM – 2:05 PM PT
Combinatory Differentiation of Human Induced Pluripotent Stem Cells Generates Thymic Epithelium That Supports Thymic Crosstalk and Directs Dendritic- and CD4/CD8 T-cell Full DevelopmentSpeaker: – Nantes Université / INSERM / CR2TI
Matthieu Giraud, PhD (he/him/his) – Nantes Université / INSERM / CR2TI ### 2203658###Speaker###Group leader, senior researcher###Nantes Université / INSERM / CR2TI###Speaker: – Nantes Université / INSERM / CR2TI
### he/him/his2:05 PM – 2:20 PM PT
Patient-derived Lung Cancer Organoids as 3d-testing Platform for Advanced Personalized TherapiesPresenting Author: – Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT)
Oral
Martí Farrera-Sal – Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT) ### 2288173###Presenting Author###Postdoctoral Scientist###Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT)###Presenting Author: – Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT)
### 2:20 PM – 2:45 PM PT
Exploiting Artificial Thymic Organoids for the Modeling of Human FOXP3+ Regulatory T Cell DevelopmentSpeaker: – Research Institute of the McGill University Health Centre
Ciriaco Piccirillo, PhD (he/him/his) – Research Institute of the McGill University Health Centre ### 738280###Speaker###Principal Investigator, Senior Scientist and Director###Research Institute of the McGill University Health Centre###Speaker: – Research Institute of the McGill University Health Centre
### he/him/his2:45 PM – 3:15 PM PT
Coffee Break
2:45 PM – 3:15 PM PT
Coffee Break
3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 2
3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 2Chair: – Stanford University
Holden T. Maecker, PhD – Stanford University ### 387249###Chair###Professor (Research)###Stanford University###Chair: – Stanford University
### 3:15 PM – 5:15 PM PT
Immune MechanismsChair: – University of Florida
3:15 PM – 5:15 PM PT
Immune MechanismsChair: – University of Florida
Todd Brusko, MD – University of Florida ### 2310147###Chair######University of Florida###Chair: – University of Florida
### 3:15 PM – 3:30 PM PT
Induction of Tolerogenic Dendritic Cell Phenotype Through Natural Killer CellsPresenting Author: – Abbvie
Basic Science of Immunology - Innate Immunity
Ammar J. Alsheikh, MD, PhD – Abbvie ### 2300060###Presenting Author###Senior Scientist###Abbvie###Presenting Author: – Abbvie
### 3:30 PM – 3:45 PM PT
Regulation and Dysregulation of Immune Responses by Human Skin Dendritic Cell SubsetPresenting Author: – Washington University in St. Louis
Basic Science of Immunology - Innate Immunity
Eynav Klechevsky, PhD – Washington University in St. Louis ### 1609032###Presenting Author###Assistant professor###Washington University in St. Louis###Presenting Author: – Washington University in St. Louis
### 3:45 PM – 4:00 PM PT
The Role of Recirculating Regulatory T Cells in Thymic RegenerationPresenting Author: – Memorial Sloan Kettering Cancer center
Stem Cell and Organ Transplantation
Andri Leo Lemarquis, PhD – Memorial Sloan Kettering Cancer center ### 2300059###Presenting Author###Postdoc###Memorial Sloan Kettering Cancer center###Presenting Author: – Memorial Sloan Kettering Cancer center
### 4:00 PM – 4:15 PM PT
Single-cell Transcriptomes Reveal Unique CD8 T Cell Atlas Induced by Cytomegalovirus Viremia in Kidney Transplant RecipientsPresenting Author: – University of California, Los Angeles
Systems Immunology
Yumeng (Angela) Sun, B.S. – University of California, Los Angeles ### 1996226###Presenting Author###Graduate Student###University of California, Los Angeles###Presenting Author: – University of California, Los Angeles
### 4:15 PM – 4:30 PM PT
Altered Intestinal Barrier and Immunoregulatory Gut-derived Metabolites Contribute to Acute Rejection in Renal TransplantationPresenting Author: – University College London
Stem Cell and Organ Transplantation
Fernando Yuen Chang, MBCHB – University College London ### 2300061###Presenting Author###PhD Student###University College London###Presenting Author: – University College London
### 4:30 PM – 4:45 PM PT
Unraveling the Mechanistic Regulation of IL-2 Signaling in T Cells and DiseasesPresenting Author: – Laboratory of Molecular Immunology, National Heart, Lung & Blood Institute, National Institutes of Health, United States
Basic Science of Immunology - Adaptive Immunity
Suyasha Roy, PhD – Laboratory of Molecular Immunology, National Heart, Lung & Blood Institute, National Institutes of Health, United States ### 2300062###Presenting Author###Post-Doctoral Fellow###Laboratory of Molecular Immunology, National Heart, Lung & Blood Institute, National Institutes of Health, United States###Presenting Author: – Laboratory of Molecular Immunology, National Heart, Lung & Blood Institute, National Institutes of Health, United States
### 4:45 PM – 5:00 PM PT
Helios Regulates CD8 T Cell Activation in Response to TCR AffinityPresenting Author: – Universidad Nacional Autonoma de Mexico
Basic Science of Immunology - Adaptive Immunity
Gerardo Suárez-Rojas – Universidad Nacional Autonoma de Mexico ### 2039553###Presenting Author###PhD Student###Universidad Nacional Autonoma de Mexico###Presenting Author: – Universidad Nacional Autonoma de Mexico
### 5:00 PM – 5:15 PM PT
Retinoic Acid Promotes Succinate-consuming Gut Bacteria to Suppress Intestinal InflammationPresenting Author: – Translational Health Science and Technology Institute
Basic Science of Immunology - Adaptive Immunity
Amit Awasthi, PhD – Translational Health Science and Technology Institute ### 2300058###Presenting Author######Translational Health Science and Technology Institute###Presenting Author: – Translational Health Science and Technology Institute
### 3:15 PM – 5:15 PM PT
Immunoengineering and TherapeuticsChair: – Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona
3:15 PM – 5:15 PM PT
Immunoengineering and TherapeuticsChair: – Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona
Ricardo Pujol Borrell, MD, PhD – Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona ### 1139670###Chair###Professor###Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona###Chair: – Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona
### 3:15 PM – 3:30 PM PT
Tolerogenic IL-2 Containing Nanoparticles Induce CD4 and CD8 Regulatory T Cells and TGF-β Producing Regulatory NK Cells That Provide Essential Support for the Tregs Which Suppress Immune-mediated DisordersPresenting Author: – General Nanotherapeutics, LLC
Immuno-engineering and Cellular Therapies
David A. Horwitz, MD – General Nanotherapeutics, LLC ### 1310167###Presenting Author###Founder###General Nanotherapeutics, LLC###Presenting Author: – General Nanotherapeutics, LLC
### 3:30 PM – 3:45 PM PT
Rosnilimab, a PD-1 Agonist Antibody That Binds to a Membrane Proximal Epitope Leading to Optimized PD-1 Agonistic SignalingPresenting Author: – AnaptysBio
Basic Science of Immunology - Adaptive Immunity
Stephen Parmley, PhD – AnaptysBio ### 751445###Presenting Author######AnaptysBio###Presenting Author: – AnaptysBio
### 3:45 PM – 4:00 PM PT
IL-10 Producing Tolerogenic Dendritic Cells Modulate B Cell Responses in vitro and in vivoPresenting Author: – San Raffaele Telethon institute for Gene Therapy
Immuno-engineering and Cellular Therapies
Silvia Gregori, PhD – San Raffaele Telethon institute for Gene Therapy ### 365554###Presenting Author###Dr###San Raffaele Telethon institute for Gene Therapy###Presenting Author: – San Raffaele Telethon institute for Gene Therapy
### 4:00 PM – 4:15 PM PT
Precision Therapy for Lupus: Targeting Follicular Helper T Cells Using Chimeric Antigen Receptor Natural Killer CellsPresenting Author: – Cincinnati Children's Hospital
Immuno-engineering and Cellular Therapies
Nora Lakes (they/them/theirs) – Cincinnati Children's Hospital ### 1945914###Presenting Author###MD-PhD student###Cincinnati Children's Hospital###Presenting Author: – Cincinnati Children's Hospital
### they/them/theirs4:15 PM – 4:30 PM PT
T-cell Receptor Precision Editing of Regulatory T-cells for Celiac DiseasePresenting Author: – Lausanne University hospital and University of Lausanne
Immuno-engineering and Cellular Therapies
Raphael Porret – Lausanne University hospital and University of Lausanne ### 1608581###Presenting Author###MD-PhD student###Lausanne University hospital and University of Lausanne###Presenting Author: – Lausanne University hospital and University of Lausanne
### 4:30 PM – 4:45 PM PT
Regeneration of a Sustained Antiviral Response in Transplant Recipients by Tacrolimus Resistant Antiviral T-cell ProductsPresenting Author: – Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany
Immuno-engineering and Cellular Therapies
Niklas Wiese – Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany ### 2041855###Presenting Author######Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany###Presenting Author: – Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany
### 4:45 PM – 5:00 PM PT
Expanding Our Understanding of PDC-E2 T Cell Responses in PBC and Their Application for Eng Treg TherapyPresenting Author: – Benaroya Research Institute
Autoimmune Diseases
Ritika Tewari, PhD – Benaroya Research Institute ### 2300054###Presenting Author###Staff Scientist###Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 5:00 PM – 5:15 PM PT
Gene-edited Allogeneic Regulatory T Cells as 'Off-the-shelf' Immunomodulatory Therapy for TransplantationPresenting Author: – Charité - Universitätsmedizin Berlin
Immuno-engineering and Cellular Therapies
Dimitrios L. Wagner, MD, PhD – Charité - Universitätsmedizin Berlin ### 740535###Presenting Author###Research Associate###Charité - Universitätsmedizin Berlin###Presenting Author: – Charité - Universitätsmedizin Berlin
### 3:15 PM – 5:15 PM PT
Immuno-oncology
3:15 PM – 5:15 PM PT
Immuno-oncology
3:15 PM – 3:30 PM PT
Spatially Exploring RNA Biology in Archival Formalin-fixed Paraffin-embedded TissuesPresenting Author: – Yale University
Systems Immunology
Zhiliang Bai, PhD – Yale University ### 2288181###Presenting Author###Postdoc Associate###Yale University###Presenting Author: – Yale University
### 3:30 PM – 3:45 PM PT
Peripheral Blood as a Source to Identify Candidate Neoantigens and Reactive TcrsPresenting Author: – Vall Hebron Oncology Institute and Universitat Autonoma de Barcelona
Immuno-oncology
Ricardo Pujol Borrell, PhD – Vall Hebron Oncology Institute and Universitat Autonoma de Barcelona ### 366553###Presenting Author###Emeritus Professor###Vall Hebron Oncology Institute and Universitat Autonoma de Barcelona###Presenting Author: – Vall Hebron Oncology Institute and Universitat Autonoma de Barcelona
### 3:45 PM – 4:00 PM PT
Helios Limits CD8 T Cell Antitumor CapacityPresenting Author: – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Immuno-oncology
Rosa M. Rubio – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran ### 2300064###Presenting Author######Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran###Presenting Author: – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
### 4:00 PM – 4:15 PM PT
Secondary Inhibitory Signals on Human Kidney Microvascular Endothelium Confer Peripheral T Cell Tolerance: insight from Checkpoint Inhibitor ToxicityPresenting Author: – University of Washington
Immuno-oncology
Kimberly Muczynski, MD-PhD – University of Washington ### 1945923###Presenting Author###Associate Professor###University of Washington###Presenting Author: – University of Washington
### 4:15 PM – 4:30 PM PT
CAR T-Cell Therapy Targeting CD84 Alone or in Combination with CD19 for the Treatment of B-Cell MalignanciesPresenting Author: – Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)
Immuno-engineering and Cellular Therapies
Ane Altuna Mongelos – Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) ### 2300156###Presenting Author######Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)###Presenting Author: – Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)
### 4:30 PM – 4:45 PM PT
HIV-associated Lung Cancer Exhibits an Immunoregulatory Tumor MicroenvironmentPresenting Author: – Yale University
Immuno-oncology
Brinda Emu, MD – Yale University ### 1319794###Presenting Author######Yale University###Presenting Author: – Yale University
### 4:45 PM – 5:00 PM PT
Exclusion of PD-1 from the Immune Synapse: A Novel Strategy to Modulate T Cell FunctionPresenter: – Columbia University
Immuno-oncology
Matthieu J. Paiola, PhD – Columbia University ### 2304241###Presenter###Associate Research Scientist###Columbia University###Presenter: – Columbia University
### 5:00 PM – 5:15 PM PT
TMEM176B Is a Druggable Intrinsic Driver of Protumoral Th17 LymphocytesPresenting Author: – Institut Pasteur de Montevideo
Immuno-oncology
Marcelo Hill, MD, PhD – Institut Pasteur de Montevideo ### 1319274###Presenting Author######Institut Pasteur de Montevideo###Presenting Author: – Institut Pasteur de Montevideo
### 5:30 PM – 5:45 PM PT
State of FOCIS
5:30 PM – 5:45 PM PT
State of FOCIS AddressLocation: Salon 8Speaker: – Columbia University
Megan Sykes, MD (she/her/hers) – Columbia University ### 366755###Speaker###Michael J. Friedlander Professor of Medicine and Professor of Microbiology & Immunology and Surgical Sciences (in Surgery), Columbia University
Director, Columbia Center for Translational Immunology, Columbia University College of Physicians and Surgeons
Director of Research, Transplant Initiative,
Director, Bone Marrow Transplantation Research, Division of Hematology/Oncology
Columbia University Medical Center
###Columbia University###Speaker: – Columbia University
### she/her/hers5:45 PM – 6:30 PM PT
Keynote Address
5:45 PM – 6:30 PM PT
Keynote Address: Title Coming SoonSpeaker: – University of Chicago
Chair: – Columbia University
Bana Jabri, MD, PhD – University of Chicago ### 906789###Speaker######University of Chicago###Speaker: – University of Chicago
### @@@ Joshua Milner, MD – Columbia University ### 1611209###Chair###Principal Investigator###Columbia University###Chair: – Columbia University
### 6:30 PM – 7:45 PM PT
Exhibits & Poster Presentations Reception
6:30 PM – 7:45 PM PT
Exhibits & Poster Presentations Reception
Location: Salon 9
- Friday, June 21, 2024
7:00 AM – 3:45 PM PT
Registration Desk Open
7:00 AM – 2:00 PM PT
Registration Desk Open
Location: Registration Desk
8:00 AM – 9:30 AM PT
Somatic Mosaicism, Clonal Populations and Immune DisordersChair: – SingHealth Duke-NUS Academic Medical Centre
8:00 AM – 9:30 AM PT
Somatic Mosaicism, Clonal Populations and Immune DisordersChair: – SingHealth Duke-NUS Academic Medical Centre
Salvatore Albani, MD, PhD – SingHealth Duke-NUS Academic Medical Centre ### 2309936###Chair######SingHealth Duke-NUS Academic Medical Centre###Chair: – SingHealth Duke-NUS Academic Medical Centre
### 8:00 AM – 8:30 AM PT
Somatic Mosaicism in Genetic Diseases of the Immune SystemSpeaker: – Washington University School in St. Louis
Megan A. Cooper, MD, PhD (she/her/hers) – Washington University School in St. Louis ### 651470###Speaker###Professor###Washington University School in St. Louis###Speaker: – Washington University School in St. Louis
### she/her/hers8:30 AM – 9:00 AM PT
From Mosaics to Clones: Aligning Terminology in Genetic VariabilitySpeaker: – Weill Cornell Medicine
Monica L. Guzman, PhD (she/her/hers) – Weill Cornell Medicine ### 751352###Speaker###Associate Professor of Pharmacology in Medicine###Weill Cornell Medicine###Speaker: – Weill Cornell Medicine
### she/her/hers9:00 AM – 9:30 AM PT
Mechanisms That Contribute Towards Female-biased Autoimmunity: X-chromosome InactivationSpeaker: – University of Pennsylvannia
Montserrat Anguera, PhD (she/her/hers) – University of Pennsylvannia ### 2203650###Speaker###Associate Professor###University of Pennsylvannia###Speaker: – University of Pennsylvannia
### she/her/hers9:30 AM – 10:00 AM PT
Coffee Break
9:30 AM – 10:00 AM PT
Coffee Break
10:00 AM – 11:30 AM PT
Mechanisms & Treatment of AutoimmunityChair: – Washington University in St. Louis
10:00 AM – 11:30 AM PT
Mechanisms & Treatment of AutoimmunityChair: – Washington University in St. Louis
Michael M. Paley – Washington University in St. Louis ### 2040065###Chair######Washington University in St. Louis###Chair: – Washington University in St. Louis
### 10:00 AM – 10:30 AM PT
Enhancing Treg Therapy Through Cell EngineeringSpeaker: – University of California, San Francisco
Qizhi Tang, PhD (she/her/hers) – University of California, San Francisco ### 365695###Speaker###Professor###University of California, San Francisco###Speaker: – University of California, San Francisco
### she/her/hers10:30 AM – 11:00 AM PT
APS-1/APECED: Mechanisms & Treatment of AutoimmunitySpeaker: – National Institute of Allergy and Infectious Diseases
Michail S. Lionakis, MD, ScD (he/him/his) – National Institute of Allergy and Infectious Diseases ### 1541312###Speaker###Chief, Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology###National Institute of Allergy and Infectious Diseases###Speaker: – National Institute of Allergy and Infectious Diseases
### he/him/his11:00 AM – 11:30 AM PT
Title Coming SoonSpeaker: – Stanford University School of Medicine
Howard Chang, M.D., Ph.D – Stanford University School of Medicine ### 389563###Speaker######Stanford University School of Medicine###Speaker: – Stanford University School of Medicine
### 11:45 AM – 12:30 PM PT
Keynote Session
11:45 AM – 12:30 PM PT
Keynote Address: Cell, Tissue and Perturbation Atlases as Roadmaps in CancerLocation: Salon 8Speaker: – Genentech
Chair: – Washington University School in St. Louis
Aviv Regev, PhD – Genentech ### 2203670###Speaker###Executive Vice President, Research and Early Development###Genentech###Speaker: – Genentech
### @@@ Megan A. Cooper, MD, PhD (she/her/hers) – Washington University School in St. Louis ### 651470###Chair###Professor###Washington University School in St. Louis###Chair: – Washington University School in St. Louis
### she/her/hers12:45 PM – 2:00 PM PT
Industry and Partner Lunch Programs
12:45 PM – 2:00 PM PT
Industry and Partner Lunch Programs
12:45 PM – 2:00 PM PT
Partner Program: NIH/NIAID
12:45 PM – 2:00 PM PT
Partner Program: Journal of Experimental Medicine – Meet the EditorSpeaker: – Journal of Experimental Medicine (JEM)
Shachi Bhatt, PhD – Journal of Experimental Medicine (JEM) ### 1678429###Speaker###Executive Editor###Journal of Experimental Medicine (JEM)###Speaker: – Journal of Experimental Medicine (JEM)
### 2:00 PM – 3:45 PM PT
Behavioral Immunology and NeuroimmunologyChair: – Mount Kenya University
2:00 PM – 3:45 PM PT
Behavioral Immunology and NeuroimmunologyChair: – Mount Kenya University
Jesse Gitaka, MD, MTM, PhD – Mount Kenya University ### 2325108###Chair######Mount Kenya University###Chair: – Mount Kenya University
### 2:00 PM – 2:25 PM PT
Sickness Behaviors of Type 2 ImmunitySpeaker: – Arizona State University
Esther Borges Florsheim, PhD – Arizona State University ### 2203651###Speaker###Assistant Professor###Arizona State University###Speaker: – Arizona State University
### 2:25 PM – 2:40 PM PT
Longitudinal Analysis of Immune Cell Changes in FUS-ALS Patients Treated with a FUS Antisense OligonucleotidePresenting Author: – Columbia University
Oral
Olivia M. Rifai, PhD – Columbia University ### 2288178###Presenting Author###Postdoctoral Fellow###Columbia University###Presenting Author: – Columbia University
### 2:40 PM – 3:05 PM PT
Unique Aspects of IFN-γ/STAT1 Signaling in NeuronsSpeaker: – Duke University/Neurosurgery/Marcus Center for Cellular Cures
Anthony Filiano, PhD – Duke University/Neurosurgery/Marcus Center for Cellular Cures ### 2203657###Speaker###Assistant Professor###Duke University/Neurosurgery/Marcus Center for Cellular Cures###Speaker: – Duke University/Neurosurgery/Marcus Center for Cellular Cures
### 3:05 PM – 3:20 PM PT
Greater Composite Confirmed Disability Progression in Non-hispanic Black and Hispanic or Latino Individuals with Relapsing Multiple Sclerosis: Analysis of Self-reported Identity and Genetic Ancestry in the OPERA I and II TrialsPresenting Author: – Genentech
Oral
Xiaoming Jia, MD MEng – Genentech ### 2288179###Presenting Author###Group Medical Director###Genentech###Presenting Author: – Genentech
### 3:20 PM – 3:45 PM PT
Sensory Neuron Regulation of Host Defense and ImmunitySpeaker: – Department of Immunology, Harvard Medical School
Isaac Chiu, PhD – Department of Immunology, Harvard Medical School ### 2203652###Speaker###Associate Professor###Department of Immunology, Harvard Medical School###Speaker: – Department of Immunology, Harvard Medical School
### 2:00 PM – 3:45 PM PT
Immuno-oncology
2:00 PM – 3:45 PM PT
2:00 PM – 2:25 PM PT
Reprogramming the Tumor-immune Microenvironment by Targeting the Galectin-glycan AxisSpeaker: – Instituto de Biología y Medicina Experimental
Gabriel Rabinovich, PhD (he/him/his) – Instituto de Biología y Medicina Experimental ### 2203669###Speaker###Head Laboratory Glycomedicine, IBYME and Professor of Immunology, University of Buenos Aires###Instituto de Biología y Medicina Experimental###Speaker: – Instituto de Biología y Medicina Experimental
### he/him/his2:25 PM – 2:40 PM PT
Pre-existing Skin-resident CD8 and γδ T Cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy EfficacyPresenting Author: – Northwestern University
Oral
Zachary Zale Reinstein – Northwestern University ### 2288171###Presenting Author######Northwestern University###Presenting Author: – Northwestern University
### 2:40 PM – 3:05 PM PT
GD2-CAR T-cell Therapy for Diffuse Midline GliomasSpeaker: – Stanford University
Michelle Monje, MD, PhD (she/her/hers) – Stanford University ### 2219549###Speaker###Professor, Neurology & Neurological Sciences ###Stanford University###Speaker: – Stanford University
### she/her/hers3:05 PM – 3:20 PM PT
Aire-expressing Tumor-associated Macrophages Promote Cancer Immune EvasionPresenting Author: – University of California San Francisco
Oral
Matthew Arvedson – University of California San Francisco ### 2288172###Presenting Author###Graduate Student###University of California San Francisco###Presenting Author: – University of California San Francisco
### 3:20 PM – 3:45 PM PT
Adipocyte-secreted interleukin-9 Promotes B-cell Acute Lymphoblastic Leukemia ProgressionSpeaker: – University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus
Curtis J. Henry, PhD (he/him/his) – University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus ### 2203660###Speaker###Deputy Associate Director of DEIA/Associate Professor of Immunology and Microbiology###University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus###Speaker: – University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus
### he/him/his2:00 PM – 3:45 PM PT
Metabolic Regulation of Inflammation
2:00 PM – 3:45 PM PT
Metabolic Regulation of Inflammation
2:00 PM – 2:25 PM PT
An Immunometabolic Circuit Triggered by Dietary ChitinSpeaker: – Washington University School of Medicine in St. Louis
Steven Van Dyken, PhD (he/him/his) – Washington University School of Medicine in St. Louis ### 2203672###Speaker###Assistant Professor###Washington University School of Medicine in St. Louis###Speaker: – Washington University School of Medicine in St. Louis
### he/him/his2:25 PM – 2:40 PM PT
Human Tolerogenic Dendritic Cells Used in Clinic Regulate CD8+ T Cell PopulationPresenting Author: – CR2TI UMR1064
Oral
Maaike Suuring, PhD – CR2TI UMR1064 ### 2288175###Presenting Author######CR2TI UMR1064###Presenting Author: – CR2TI UMR1064
### 2:40 PM – 3:05 PM PT
Integrating Systems Immunology with Metabolism and CancerSpeaker: – St. Jude Children's Research Hospital
Hongbo Chi, PhD – St. Jude Children's Research Hospital ### 651468###Speaker###Member###St. Jude Children's Research Hospital###Speaker: – St. Jude Children's Research Hospital
### 3:05 PM – 3:20 PM PT
Skeletal Muscle DUPD1 Links Gut Inflammation with Obesity-associated Metabolic DiseasesPresenting Author: – University of Toronto
Oral
Alberto Martin, PhD (he/him/his) – University of Toronto ### 985585###Presenting Author###Professor###University of Toronto###Presenting Author: – University of Toronto
### he/him/his3:20 PM – 3:45 PM PT
Immunometabolism at the Crossroads Between Inflammation and AgingSpeaker: – Molecular Biology Center, CBM, CSIC
Maria Mittelbrunn, PhD – Molecular Biology Center, CBM, CSIC ### 2203665###Speaker###Head of Immunometabolism and Inflamamtion Lab###Molecular Biology Center, CBM, CSIC###Speaker: – Molecular Biology Center, CBM, CSIC
###
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