- Monday, June 17, 2024
7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
7:30 AM – 5:00 PM PT
Systems Immunology Course (Separate Registration Required)
7:30 AM – 5:00 PM PT
Systems Immunology Course (Separate Registration Required)Location: Salons 10/11Chair: – Sanofi
Chair: – Roche
Emanuele de Rinaldis – Sanofi ### 2038981###Chair######Sanofi###Chair: – Sanofi
### @@@ Magnus Fontes, Ph.D. – Roche ### 751322###Chair######Roche###Chair: – Roche
### - Tuesday, June 18, 2024
7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
7:30 AM – 12:00 PM PT
Big Data in Immunology Workshop (Separate Registration Required)
7:30 AM – 12:00 PM PT
Big Data in Immunology Workshop (Separate Registration Required)Location: Salons 10/11Chair: – University of California, San Francisco
Sanchita Bhattacharya, PhD – University of California, San Francisco ### 365757###Chair###Bioinformatics Project Leader###University of California, San Francisco###Chair: – University of California, San Francisco
### 8:00 AM – 11:30 AM PT
Member Society Symposia
8:00 AM – 11:30 AM PT
Member Society Symposia
8:00 AM – 9:30 AM PT
Immunity at the Intestinal BarrierLocation: Salons 3/4
8:00 AM – 11:30 AM PT
Crosstalk Between Stress and ImmunityLocation: Salons 5/6
8:00 AM – 11:30 AM PT
Investigating Common Mechanisms of AutoimmunityLocation: Salon 7
8:00 AM – 11:30 AM PT
New Frontiers in B Cell/Antibody ResponsesLocation: Salons 12/13
10:00 AM – 11:30 AM PT
Immune Responses at the Barrier Sites Through the Lenses of New Nomenclature of Allergy and Clinical ImmunologyLocation: Salons 3/4
8:00 AM – 5:15 PM PT
Basic Immunology in Medicine Course (Separate Registration Required)
8:00 AM – 5:15 PM PT
Basic Immunology in Medicine Course (Separate Registration Required)Location: Nob Hill A-DChair: – University of California, San Francisco
Chair: – University of California, San Francisco
Sponsored By Autoimmune Association, Grifols
Abul Abbas, MD – University of California, San Francisco ### 751324###Chair######University of California, San Francisco###Chair: – University of California, San Francisco
### @@@ Mark Anderson, MD, PhD – University of California, San Francisco ### 435351###Chair###Professor and Director, UCSF Diabetes Center###University of California, San Francisco###Chair: – University of California, San Francisco
### 9:30 AM – 10:30 AM PT
Coffee Break
9:30 AM – 10:30 AM PT
Coffee Break
Location: Yerba Buena Grand Assembly
1:30 PM – 5:00 PM PT
Member Society Symposia
1:30 PM – 5:00 PM PT
Member Society Symposia
1:30 PM – 3:00 PM PT
Advances in Mast Cell ResearchLocation: Salons 3/4
1:30 PM – 3:00 PM PT
Interaction Between Environmental Factors and Immune System in Immune-mediated DiseasesLocation: Salons 10/11
1:30 PM – 5:00 PM PT
APS1 and Immune Tolerance: From Basic Biology to Clinical TranslationLocation: Salons 5/6
1:30 PM – 5:00 PM PT
Expanding and Unlocking the Tools of Immunotherapy to Improve Understanding and Treatment for Cancer, Autoimmune Disease and TransplantationLocation: Salon 7
1:30 PM – 5:00 PM PT
Latin-American Immunologists SymposiumLocation: Salons 12/13
3:30 PM – 5:00 PM PT
IL-9: From Birth to BreathLocation: Salons 3/4
3:30 PM – 5:00 PM PT
The Environment, Air Pollution, Microbiome and Allergy and Vaccines in Transplant PatientsLocation: Salons 10/11
3:00 PM – 3:30 PM PT
Coffee Break
3:00 PM – 3:30 PM PT
Coffee Break
Location: Yerba Buena Grand Assembly
5:30 PM – 6:15 PM PT
Keynote Session
5:30 PM – 6:15 PM PT
Opening Keynote Address: XenotransplantationLocation: Salon 8Speaker: – New York University Langone Health
Chair: – Columbia University
Robert A. Montgomery, MD, D.Phil, FACS (he/him/his) – New York University Langone Health ### 2203666###Speaker###H. Leon Pachter Chair & Professor of Surgery###New York University Langone Health###Speaker: – New York University Langone Health
### he/him/his @@@ Megan Sykes, MD (she/her/hers) – Columbia University ### 366755###Chair###Michael J. Friedlander Professor of Medicine and Professor of Microbiology & Immunology and Surgical Sciences (in Surgery), Columbia UniversityDirector, Columbia Center for Translational Immunology, Columbia University College of Physicians and SurgeonsDirector of Research, Transplant Initiative, Director, Bone Marrow Transplantation Research, Division of Hematology/OncologyColumbia University Medical Center###Columbia University###Chair: – Columbia University
### she/her/hers6:15 PM – 7:30 PM PT
Opening Reception: Exhibits & Poster Presentations
6:15 PM – 7:30 PM PT
Exhibit and Poster Opening ReceptionLocation: Salon 9
- Wednesday, June 19, 2024
7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
Location: Salon 9
7:30 AM – 7:30 PM PT
Exhibition & Poster Hall Open (authors optional)
7:30 AM – 7:30 PM PT
Exhibition & Poster Hall Open (authors Optional)
Location: Salon 9
8:00 AM – 9:30 AM PT
Novel Pathways and Approaches in Allergic DiseaseChair: – Northwestern University
8:00 AM – 9:30 AM PT
Novel Pathways and Approaches in Allergic DiseaseLocation: Salon 8Chair: – Northwestern University
Stephanie C. Eisenbarth, MD, PhD – Northwestern University ### 2311253###Chair######Northwestern University###Chair: – Northwestern University
### 8:00 AM – 8:30 AM PT
Repurposing Approved Bruton’s Tyrosine Kinase Inhibitors for the Prevention of AnaphylaxisLocation: Salon 8Speaker: – Johns Hopkins University School of Medicine
Melanie C. Dispenza, MD, PhD (she/her/hers) – Johns Hopkins University School of Medicine ### 2203654###Speaker###Assistant Professor of Medicine###Johns Hopkins University School of Medicine###Speaker: – Johns Hopkins University School of Medicine
### she/her/hers8:30 AM – 9:00 AM PT
Computational Engineering of Major Allergens to Reduce Allergenicity and Maintain Immunogenicity Enables Safe and Effective Immunotherapy for Food AllergyLocation: Salon 8
Yanay Ofran, PhD – Ukko, Inc. ### 1541307###Speaker###Founder###Ukko, Inc.###Speaker: – Ukko, Inc.
### 9:00 AM – 9:30 AM PT
Regulation of Allergic Responses to Food by Commensal Bacterial Products and MetabolitesLocation: Salon 8Speaker: – University of Chicago
Cathryn Nagler, PhD (she/her/hers) – University of Chicago ### 308427###Speaker###Professor###University of Chicago###Speaker: – University of Chicago
### she/her/hers9:30 AM – 10:00 AM PT
Coffee Break
9:30 AM – 10:00 AM PT
Coffee Break
Location: Yerba Buena Grand Assembly
10:00 AM – 11:30 AM PT
Precision Therapeutics in Mucosal DisordersChair: – Washington University School in St. Louis
10:00 AM – 11:30 AM PT
Precision Therapeutics in Mucosal DisordersLocation: Salon 8Chair: – Washington University School in St. Louis
Eynav Klechevsky, PhD – Washington University School in St. Louis ### 1609032###Chair###Assistant professor###Washington University School in St. Louis###Chair: – Washington University School in St. Louis
### 10:00 AM – 10:30 AM PT
Microbial Host Defense and Influence in CancerLocation: Salon 8Speaker: – University of Texas MD Anderson Cancer Center
Florencia McAllister, MD – University of Texas MD Anderson Cancer Center ### 2203663###Speaker###Associate Professor###University of Texas MD Anderson Cancer Center###Speaker: – University of Texas MD Anderson Cancer Center
### 10:30 AM – 11:00 AM PT
Unexpected Mechanisms Regulating Allergen Absorption from the GutLocation: Salon 8Speaker: – Northwestern University
Stephanie C. Eisenbarth, MD, PhD – Northwestern University ### 2311253###Speaker######Northwestern University###Speaker: – Northwestern University
### 11:00 AM – 11:30 AM PT
Microbiome Therapies in Food AllergyLocation: Salon 8Speaker: – Boston Children's Hospital
Rima Rachid, MD (she/her/hers) – Boston Children's Hospital ### 2232700###Speaker###Co-Director, Food Allergy Program###Boston Children's Hospital###Speaker: – Boston Children's Hospital
### she/her/hers11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:30 AM – 1:00 PM PT
2024 Lupus Insight Prize Award Ceremony and LuncheonLocation: Nob Hill A-DChair:
Speaker: – The University of Tennessee Health Science Center
Speaker: – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen
Andrew Chan, MD, PhD ### 2364831###Chair#########Chair:
### @@@ Marko Radic, PhD – The University of Tennessee Health Science Center ### 2364832###Speaker######The University of Tennessee Health Science Center###Speaker: – The University of Tennessee Health Science Center
### @@@ Georg Schett, MD – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen ### 2311714###Speaker######Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen###Speaker: – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen
### 11:45 AM – 1:00 PM PT
Industry Tutorial: Optimized immunophenotyping with high dimensional spectral flow cytometry panelsLocation: Salons 12/13
Zayda Piedra, PhD ### 2317893###Speaker#########Speaker:
### 1:00 PM – 2:45 PM PT
Immune Responses to GT/TherapeuticsChair: – University of British Columbia
1:00 PM – 2:45 PM PT
Immune Responses to GT/TherapeuticsLocation: Salon 7Chair: – University of British Columbia
Megan K. Levings, PhD (she/her/hers) – University of British Columbia ### 365464###Chair###Professor###University of British Columbia###Chair: – University of British Columbia
### she/her/hers1:00 PM – 1:25 PM PT
Human Immune Responses to Viral Gene Therapy VectorsLocation: Salon 7Speaker: – Nava Therapeutics
Federico Mingozzi, PhD (he/him/his) – Nava Therapeutics ### 2203664###Speaker###CEO###Nava Therapeutics###Speaker: – Nava Therapeutics
### he/him/his1:25 PM – 1:40 PM PT
PanTreg: A Cell-therapy, System-biology - Based Approach for Therapy of AutoimmunityLocation: Salon 7Presenting Author: – Translational Immunology Institute, SingHealth
Oral
Salvatore Albani, MD, PhD – Translational Immunology Institute, SingHealth ### 365688###Presenting Author###Director###Translational Immunology Institute, SingHealth###Presenting Author: – Translational Immunology Institute, SingHealth
### 1:40 PM – 2:05 PM PT
Preclinical and Clinical Development of Tolerogenic Immtor Nanoparticles to Mitigate Immunogenicity of Biologic and Gene TherapiesLocation: Salon 7Speaker: – Selecta Biosciences
Kei Kishimoto, PhD (he/him/his) – Selecta Biosciences ### 366581###Speaker###former CSO###Selecta Biosciences###Speaker: – Selecta Biosciences
### he/him/his2:05 PM – 2:20 PM PT
CAR-Ts Are Getting Viral! a New Method for Allogenic CAR-T Cell Therapy DevelopmentLocation: Salon 7Presenting Author: – IDIBAPS
Oral
Mario Vazquez – IDIBAPS ### 2288177###Presenting Author######IDIBAPS###Presenting Author: – IDIBAPS
### 2:20 PM – 2:45 PM PT
Derivation of Clinically Relevant T-lymphocytes from Human iPSCLocation: Salon 7Speaker: – Boston University
Gustavo Mostoslavsky, MD, PhD (he/him/his) – Boston University ### 1139704###Speaker###Professor of Medicine###Boston University###Speaker: – Boston University
### he/him/his1:00 PM – 2:45 PM PT
Inborn Errors of ImmunityChair: – University of Colorado
1:00 PM – 2:45 PM PT
Inborn Errors of ImmunityLocation: Salons 3-6Chair: – University of Colorado
Elena WY Hsieh, MD – University of Colorado ### 1608904###Chair###Associate Professor###University of Colorado###Chair: – University of Colorado
### 1:00 PM – 1:25 PM PT
Human Cytosolic Double-stranded RNA Sensors and SARS-COV-2 SusceptibilityLocation: Salons 3-6
Helen C. Su, MD, PhD – NIH/NIAID ### 741312###Speaker###Chief, Human Immunological Diseases Section###NIH/NIAID###Speaker: – NIH/NIAID
### 1:25 PM – 1:40 PM PT
STAT1 Gain-of-function Leads to Dysfunctional T Regulatory CellsLocation: Salons 3-6Presenting Author: – University of California San Francisco
Oral
Martin Thelin, MD, PhD – University of California San Francisco ### 2288176###Presenting Author######University of California San Francisco###Presenting Author: – University of California San Francisco
### 1:40 PM – 2:05 PM PT
Gene Therapy for Wiskott-aldrich SyndromeLocation: Salons 3-6Speaker: – Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute
Sung-Yun Pai, MD (she/her/hers) – Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute ### 2203668###Speaker###Chief and Senior Investigator###Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute###Speaker: – Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute
### she/her/hers2:05 PM – 2:20 PM PT
Human OTULIN Mutations Can Cause Distinct Inflammatory Disease Phenotypes Depending on the Protein Domain That Is MutatedLocation: Salons 3-6Presenting Author: – Vanderbilt University Medical Center
Oral
Hwi Gil – Vanderbilt University Medical Center ### 2288170###Presenting Author######Vanderbilt University Medical Center###Presenting Author: – Vanderbilt University Medical Center
### 2:20 PM – 2:45 PM PT
From Mechanisms of Rare Inborn Errors of Immunity to Pathway-specific Therapy in Common Autoimmune DisordersLocation: Salons 3-6Speaker: – University of Colorado
Elena WY Hsieh, MD – University of Colorado ### 1608904###Speaker###Associate Professor###University of Colorado###Speaker: – University of Colorado
### 1:00 PM – 2:45 PM PT
Systems Immunology & AI Chair: – Brigham and Women's Hospital
1:00 PM – 2:45 PM PT
Systems Immunology & AILocation: Salon 8Chair: – Brigham and Women's Hospital
Deepak A. Rao, MD, PhD – Brigham and Women's Hospital ### 651483###Chair###Assistant Professor of Medicine###Brigham and Women's Hospital###Chair: – Brigham and Women's Hospital
### 1:00 PM – 1:25 PM PT
Conserved Spatial Programs of Immune Regulation in Human Health and DiseaseLocation: Salon 8Speaker: – Stanford University
Michael Angelo, MD, PhD – Stanford University ### 985973###Speaker###Associate Professor###Stanford University###Speaker: – Stanford University
### 1:25 PM – 1:40 PM PT
Epigenetic Signature and Key Transcriptional Regulators of Human Antigen-inducible Regulatory T CellsLocation: Salon 8Presenting Author: – Stanford University
Oral
Alma-Martina Cepika, MD, PhD – Stanford University ### 1310188###Presenting Author###Instructor###Stanford University###Presenting Author: – Stanford University
### 1:40 PM – 2:05 PM PT
Single-cell to Tissue-scale Memory in the NoseLocation: Salon 8Speaker: – Boston Children's Hospital
José Ordovas-Montanes, PhD – Boston Children's Hospital ### 987320###Speaker###Assistant Professor###Boston Children's Hospital###Speaker: – Boston Children's Hospital
### 2:05 PM – 2:20 PM PT
Unsupervised and Supervised Machine Learning Promotes Translational Research of Autoimmune DiseasesLocation: Salon 8Presenting Author: – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre
Oral
Martin Wasser, PhD – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre ### 1945837###Presenting Author###Principal Biostatistician###Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre###Presenting Author: – Translational Immunology Institute/Singhealth DukeNUS Academic Medical Centre
### 2:20 PM – 2:45 PM PT
T Cell Immunity in the Acute Myeloid Leukemia Bone MarrowLocation: Salon 8Speaker: – Memorial Sloan Kettering Cancer Center
Susan De Wolf, MD – Memorial Sloan Kettering Cancer Center ### 2203653###Speaker###Assistant Attending ###Memorial Sloan Kettering Cancer Center###Speaker: – Memorial Sloan Kettering Cancer Center
### 2:45 PM – 3:15 PM PT
Coffee Break
2:45 PM – 3:15 PM PT
Coffee Break
Location: Yerba Buena Grand Assembly
3:15 PM – 5:15 PM PT
Autoimmunity and TransplantationChair: – University of Rouen Normandy
3:15 PM – 5:15 PM PT
Autoimmunity and TransplantationLocation: Salon 8Chair: – University of Rouen Normandy
Olivier Boyer, MD, PhD – University of Rouen Normandy ### 986295###Chair######University of Rouen Normandy###Chair: – University of Rouen Normandy
### 3:15 PM – 3:30 PM PT
The Role of Recipient γδ T Cells in Graft Rejection After Human Intestinal TransplantationLocation: Salon 8Presenting Author: – Columbia University
Stem Cell and Organ Transplantation
Jianing Fu, PhD – Columbia University ### 987248###Presenting Author###Assistant Professor of Medical Sciences (in Medicine), Principal Investigator###Columbia University###Presenting Author: – Columbia University
### 3:30 PM – 3:45 PM PT
Inferring Disease Mechanisms in Lupus Nephritis: lessons from the Accelerating Medicines Partnership (AMP) in SLE ConsortiumLocation: Salon 8Presenting Author: – The Feinstein Institutes for Medical Research
Autoimmune Diseases
Arnon Arazi, PhD – The Feinstein Institutes for Medical Research ### 1945809###Presenting Author###Assistant Professor###The Feinstein Institutes for Medical Research###Presenting Author: – The Feinstein Institutes for Medical Research
### 3:45 PM – 4:00 PM PT
High Dimensional, Single Cell Analysis of Epstein Barr Virus (EBV)-Specific T Cells from Pediatric Transplant Recipients with EBV Dnaemia or Controlled InfectionLocation: Salon 8Presenting Author: – Stanford University
Stem Cell and Organ Transplantation
Edward A. Vizcarra, PhD – Stanford University ### 2300053###Presenting Author###Postdoctoral Fellow###Stanford University###Presenting Author: – Stanford University
### 4:00 PM – 4:15 PM PT
Immunophenotypic Profiling Reveals Novel T Cell Subset Associated with “tolerance” in Pediatric Transplant RecipientsLocation: Salon 8Presenting Author: – Stanford University
Stem Cell and Organ Transplantation
Wenming Zhang, PhD – Stanford University ### 741090###Presenting Author######Stanford University###Presenting Author: – Stanford University
### 4:15 PM – 4:30 PM PT
Pharmacodynamic Demonstration of Immunological Tolerance Induced by KAN-101, a Novel Liver-targeted Therapy for Celiac DiseaseLocation: Salon 8Presenting Author: – Anokion
Autoimmune Diseases
Kristie M. Grebe, PhD – Anokion ### 2300057###Presenting Author###Chief Scientific Officer###Anokion###Presenting Author: – Anokion
### 4:30 PM – 4:45 PM PT
Single Cell Analysis of CD8 T-cells Reveals Autoantigen Specific Signatures of Teplizumab Treatment in at Risk Subjects from the trialnet-10 StudyLocation: Salon 8Presenting Author: – Benaroya Research Institute
Autoimmune Diseases
Hai T. Nguyen, PhD – Benaroya Research Institute ### 519951###Presenting Author###Research Scientist###Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 4:45 PM – 5:00 PM PT
BiTEing Multi-drug Resistant Rheumatoid Arthritis with CD19-T Cell EngagersLocation: Salon 8Presenting Author: – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen
Autoimmune Diseases
Ricardo Grieshaber-Bouyer, MD – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen ### 2300065###Presenting Author######Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen###Presenting Author: – Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen
### 5:00 PM – 5:15 PM PT
Donor-specific T Cell Activation and Expansion Following a Pig-to-human Decedent Kidney TransplantLocation: Salon 8Presenting Author: – Columbia University
Stem Cell and Organ Transplantation
Farshid Fathi, PhD – Columbia University ### 2039349###Presenting Author###Post Doc###Columbia University###Presenting Author: – Columbia University
### 3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 1
3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 1Location: Salons 10/11Chair: – Stanford University
Speaker:
Speaker:
Speaker:
Holden T. Maecker, PhD – Stanford University ### 387249###Chair###Professor (Research)###Stanford University###Chair: – Stanford University
### @@@ Kavita Mathi ### 2336844###Speaker#########Speaker:
### @@@ Nikolay Samusik ### 2336845###Speaker#########Speaker:
### @@@ Helen Smith ### 2336846###Speaker#########Speaker:
### 3:15 PM – 5:15 PM PT
ImmunogeneticsChair: – University of California, Los Angeles
3:15 PM – 5:15 PM PT
ImmunogeneticsLocation: Salon 7Chair: – University of California, Los Angeles
Elaine F. Reed, PhD, D(ABHI) – University of California, Los Angeles ### 366880###Chair###Professor###University of California, Los Angeles###Chair: – University of California, Los Angeles
### 3:15 PM – 3:30 PM PT
Local Intestinal Eosinophilic Activation Triggered by Defective Epithelial TGF-β Signaling Underlies IPO8 DeficiencyLocation: Salon 7Presenting Author: – Institut imagine
Allergy
Marianna Parlato, PhD – Institut imagine ### 2300050###Presenting Author######Institut imagine###Presenting Author: – Institut imagine
### 3:30 PM – 3:45 PM PT
CLEC16A-driven Mitophagy Limits Astrocyte Proinflammatory ActivitiesLocation: Salon 7Presenting Author: – Osaka University
Neuroimmunology
Atsushi Kadowaki, MD, PhD – Osaka University ### 2300051###Presenting Author######Osaka University###Presenting Author: – Osaka University
### 3:45 PM – 4:00 PM PT
Single-cell RNA-seq Analysis of PBMCs of Three Cameroonian Populations Reveals Differences in Cell Type Distribution as Well as Differentially Expressed GenesLocation: Salon 7Presenting Author: – University of Pennsylvania
Systems Immunology
Etiena Basner Tschakarjan, MD PhD – University of Pennsylvania ### 2300056###Presenting Author######University of Pennsylvania###Presenting Author: – University of Pennsylvania
### 4:00 PM – 4:15 PM PT
Intra-clonal Diversity of Donor Specific B Cell IgH Is Associated with Pathogenic Allo-immunityLocation: Salon 7Presenting Author: – University of Michigan
Stem Cell and Organ Transplantation
Marilia Cascalho, MD PhD – University of Michigan ### 1996180###Presenting Author###Professor###University of Michigan###Presenting Author: – University of Michigan
### 4:15 PM – 4:30 PM PT
Oral Pathobionts Promote CRC Development by Alteration of the Host Epigenome and Immunomic MicroenvironmentLocation: Salon 7Presenting Author: – Mayo Clinic
Mucosal Immunology
Shirin Eyvazi Khasraghi, MSc/ PhD – Mayo Clinic ### 2300052###Presenting Author###Postdoctoral Fellow###Mayo Clinic###Presenting Author: – Mayo Clinic
### 4:30 PM – 4:45 PM PT
Mechanistic Investigation of Human DPP9 DeficiencyLocation: Salon 7Presenting Author: – Yale University
Immunogenetics
Tianli Xiao, Ph.D – Yale University ### 2300063###Presenting Author###Postdoctoral fellow###Yale University###Presenting Author: – Yale University
### 4:45 PM – 5:00 PM PT
Abnormal STAT3 Signaling in Fibroblasts Promotes Staphylococcal Growth and Abnormal Tissue Response to InfectionLocation: Salon 7Presenting Author: – Columbia University
Infectious Diseases
Miao Chen, PhD – Columbia University ### 2300055###Presenting Author###Postdoc Research Scientist###Columbia University###Presenting Author: – Columbia University
### 5:00 PM – 5:15 PM PT
Genome-wide Autoimmune Genetic Variant Perturbations Connect Genetic Risk to Primary T Cell Expression and FunctionLocation: Salon 7Presenting Author: – Benaroya Research Institute
Immunogenetics
John Ray, PhD – Benaroya Research Institute ### 534435###Presenting Author###Assistant Member###Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 3:15 PM – 5:15 PM PT
Late-Breaking AbstractsChair: – Journal of Experimental Medicine (JEM)
3:15 PM – 5:15 PM PT
Late-Breaking AbstractsLocation: Salons 3-6Chair: – Journal of Experimental Medicine (JEM)
Shachi Bhatt, PhD – Journal of Experimental Medicine (JEM) ### 1678429###Chair###Executive Editor###Journal of Experimental Medicine (JEM)###Chair: – Journal of Experimental Medicine (JEM)
### 3:15 PM – 3:30 PM PT
Cellular Iron Is a Critical Regulator of ILC2 Metabolic Function and Development of Airway HyperreactivityLocation: Salons 3-6Presenting Author: – University of Southern California
Allergy
Benjamin Hurrell, PhD – University of Southern California ### 1945953###Presenting Author######University of Southern California###Presenting Author: – University of Southern California
### 3:30 PM – 3:45 PM PT
A Bispecific CD8-dependent Immunoconjugate to Crosslink and Eliminate Antigen-specific B CellsLocation: Salons 3-6Presenting Author: – Uniformed Services University of Health Sciences
Immuno-engineering and Cellular Therapies
David W. Scott, PhD – Uniformed Services University of Health Sciences ### 2332650###Presenting Author###Professor of Medicine, Emeritus###Uniformed Services University of Health Sciences###Presenting Author: – Uniformed Services University of Health Sciences
### 3:45 PM – 4:00 PM PT
A Multi-Modal Longitudinal Model of Sepsis Reveals Immune Dynamics Associated with Mild, Severe and Fatal DiseaseLocation: Salons 3-6Presenting Author: – Technion Faculty of Medicine
Infectious Diseases
Tslil Regev-Paska, M.D – Technion Faculty of Medicine ### 2332651###Presenting Author###Ph.D candidate###Technion Faculty of Medicine###Presenting Author: – Technion Faculty of Medicine
### 4:00 PM – 4:15 PM PT
Repeated Exposure to SARS-CoV-2 Antigens Induces Exceptionally Broad and Potent Neutralizing Immunity to Major Sarbecoviruses in Humans Including SARS-CoV-1Location: Salons 3-6 Author: – Tsinghua University
Infectious Diseases
Linqi Zhang, PhD (he/him/his) – Tsinghua University ### 2203676### Author###Professor###Tsinghua University### Author: – Tsinghua University
### he/him/his4:15 PM – 4:30 PM PT
A Novel Exosite Inhibitor that Selectively Reprograms TBK1-STING Pathway for Autoimmune DiseasesLocation: Salons 3-6Presenting Author: – Exo Therapeutics
Autoimmune Diseases
Bhavatarini Vangamudi, PhD – Exo Therapeutics ### 2332653###Presenting Author###Senior Director###Exo Therapeutics###Presenting Author: – Exo Therapeutics
### 4:30 PM – 4:45 PM PT
NK-mediated Protection Against Tumor Recurrence in CMV+ Bladder Cancer Patients Upon BCG TreatmentLocation: Salons 3-6Presenting Author: – Icahn School of Medicine at Mount Sinai, Genentech
Immuno-oncology
Berengere Salome, PharmD, PhD – Icahn School of Medicine at Mount Sinai, Genentech ### 2332654###Presenting Author######Icahn School of Medicine at Mount Sinai, Genentech###Presenting Author: – Icahn School of Medicine at Mount Sinai, Genentech
### 4:45 PM – 5:00 PM PT
Unraveling TIM-3 as a Myeloid Immune Checkpoint in Autoinflammatory DiseasesLocation: Salons 3-6Presenting Author: – Yale University
Neuroimmunology
Alice C. Yi – Yale University ### 2332656###Presenting Author######Yale University###Presenting Author: – Yale University
### 5:00 PM – 5:15 PM PT
Engineering Stable and Lymphodepletion-resistant T Regulatory Cells for Inducing Immune Tolerance During TransplantationLocation: Salons 3-6Presenting Author: – Mayo Clinic
Immuno-engineering and Cellular Therapies
Sameena Nikhat, PhD – Mayo Clinic ### 2332655###Presenting Author###Research Fellow###Mayo Clinic###Presenting Author: – Mayo Clinic
### 5:30 PM – 6:15 PM PT
Keynote Session - Robert B. Nussenblatt Presidential Lecture
5:30 PM – 6:15 PM PT
Keynote Address - Robert. B. Nussenblatt Presidential Lecture: Human Auto-, Allo- and Xeno-reactive T Cell Repertoire Dynamics and TranscriptomicsLocation: Salon 8Speaker: – Columbia University
Chair: – Nantes University
Megan Sykes, MD (she/her/hers) – Columbia University ### 366755###Speaker###Michael J. Friedlander Professor of Medicine and Professor of Microbiology & Immunology and Surgical Sciences (in Surgery), Columbia UniversityDirector, Columbia Center for Translational Immunology, Columbia University College of Physicians and SurgeonsDirector of Research, Transplant Initiative, Director, Bone Marrow Transplantation Research, Division of Hematology/OncologyColumbia University Medical Center###Columbia University###Speaker: – Columbia University
### she/her/hers @@@ Ignacio Anegon, MD – Nantes University ### 2040761###Chair######Nantes University###Chair: – Nantes University
### 6:15 PM – 7:30 PM PT
Exhibit and Poster Reception
6:15 PM – 7:30 PM PT
Exhibit and Poster ReceptionLocation: Salon 9
7:30 PM – 8:30 PM PT
FOCIS Member Reception (FOCIS members only)
7:30 PM – 8:30 PM PT
FOCIS Member Reception (FOCIS Members Only)Location: SoMa
- Thursday, June 20, 2024
7:00 AM – 8:00 AM PT
Conversation of Inclusion and Representation: Who is Navigating and Networking at Conferences
7:00 AM – 8:00 AM PT
Conversation of Inclusion and Representation: Who is Navigating and Networking at Conferences Location: Nob Hill A-DChair: – Weill Cornell Medicine
Monica L. Guzman, PhD (she/her/hers) – Weill Cornell Medicine ### 751352###Chair###Associate Professor of Pharmacology in Medicine###Weill Cornell Medicine###Chair: – Weill Cornell Medicine
### she/her/hers7:00 AM – 5:00 PM PT
Registration Desk Open
7:00 AM – 5:00 PM PT
Registration Desk Open
Location: Registration Desk
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
7:30 AM – 8:00 AM PT
Coffee with the Exhibitors
Location: Salon 9
7:30 AM – 7:45 PM PT
Exhibition & Poster Hall Open (authors optional)
7:30 AM – 7:45 PM PT
Exhibition & Poster Hall Open (authors Optional)
Location: Salon 9
8:00 AM – 9:30 AM PT
NeuroimmunologyChair: – Inserm U1234, FCE PAn'THER
8:00 AM – 9:30 AM PT
NeuroimmunologyLocation: Salon 8Chair: – Inserm U1234, FCE PAn'THER
Catalina Abad, PhD – Inserm U1234, FCE PAn'THER ### 741068###Chair###Research engineer###Inserm U1234, FCE PAn'THER###Chair: – Inserm U1234, FCE PAn'THER
### 8:00 AM – 8:30 AM PT
Interrogating Antigen-specific T Cell Responses in Neurodegenerative DisordersLocation: Salon 8Speaker: – Columbia University
Wassim Elyaman, PhD – Columbia University ### 738506###Speaker###Assistant Professor###Columbia University###Speaker: – Columbia University
### 8:30 AM – 9:00 AM PT
Autologous Cell Therapy for Parkinson’s Disease: From Bench to Bed and from Bed to BenchLocation: Salon 8Speaker: – McLean Hospital/Harvard University
Kwang-Soo Kim, PhD – McLean Hospital/Harvard University ### 2203662###Speaker###Professor and Director###McLean Hospital/Harvard University###Speaker: – McLean Hospital/Harvard University
### 9:00 AM – 9:30 AM PT
The Role of the Immune System in A-synucleinopathiesLocation: Salon 8Speaker: – University of Alabama at Birmingham
Ashley S. Harms, PhD (she/her/hers) – University of Alabama at Birmingham ### 2203659###Speaker###Associate Professor###University of Alabama at Birmingham###Speaker: – University of Alabama at Birmingham
### she/her/hers9:30 AM – 10:00 AM PT
Coffee Break
9:30 AM – 10:00 AM PT
Coffee Break
Location: Salon 9
10:00 AM – 11:30 AM PT
Immunology in Reproductive HealthChair: – National University of Cordoba, CIBICI-CONICET
10:00 AM – 11:30 AM PT
Immunology in Reproductive HealthLocation: Salon 8Chair: – National University of Cordoba, CIBICI-CONICET
Rubén D. Motrich – National University of Cordoba, CIBICI-CONICET ### 2310091###Chair######National University of Cordoba, CIBICI-CONICET###Chair: – National University of Cordoba, CIBICI-CONICET
### 10:00 AM – 10:30 AM PT
Immunology Learned from Mothers and BabiesLocation: Salon 8Speaker: – University of Cincinnati
Sing Sing Way, MD, PhD – University of Cincinnati ### 2203674###Speaker######University of Cincinnati###Speaker: – University of Cincinnati
### 10:30 AM – 11:00 AM PT
Immune Communication Between Mother and Fetus During Pregnancy and Its Long Term ConsequencesLocation: Salon 8Speaker: – Helmholtz Centre for Environmental Research-UFZ
Ana C. Zenclussen, PhD (she/her/hers) – Helmholtz Centre for Environmental Research-UFZ ### 2203675###Speaker###Head of the Department Environmental Immunology###Helmholtz Centre for Environmental Research-UFZ###Speaker: – Helmholtz Centre for Environmental Research-UFZ
### she/her/hers11:00 AM – 11:30 AM PT
Harnessing Maternal-Fetal Immunobiology to Prevent Preterm Birth and Identify At-Risk WomenLocation: Salon 8Speaker: – Washington University in St. Louis
Nardhy Gomez-Lopez, PhD – Washington University in St. Louis ### 2391840###Speaker######Washington University in St. Louis###Speaker: – Washington University in St. Louis
### 11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:30 AM – 1:00 PM PT
Industry and Partner Lunch Programs
11:45 AM – 1:00 PM PT
Industry Tutorial: Comprehensive Protein Profiling of Inflammation at Attomolar Sensitivity Provides Novel Insights into Mechanisms of Immune ResponseLocation: Salons 12/13Speaker: – Alamar Biosciences
Speaker: – Stanford University
Christopher Bunker, PhD, MBA – Alamar Biosciences ### 1995684###Speaker######Alamar Biosciences###Speaker: – Alamar Biosciences
### @@@ Holden T. Maecker, PhD – Stanford University ### 387249###Speaker###Professor (Research)###Stanford University###Speaker: – Stanford University
### 1:00 PM – 2:45 PM PT
Cellular & Stem Cell TherapeuticsChair: – Nantes University
1:00 PM – 2:45 PM PT
Cellular & Stem Cell TherapeuticsLocation: Salon 7Chair: – Nantes University
Ignacio Anegon, MD – Nantes University ### 2040761###Chair######Nantes University###Chair: – Nantes University
### 1:00 PM – 1:25 PM PT
Protecting Transplanted Cells from Immune Rejection Is the Key to Unlocking the Potential of Regenerative MedicineLocation: Salon 7Speaker: – Sana Biotechnology
Sonja Schrepfer, MD, PhD (she/her/hers) – Sana Biotechnology ### 2203671###Speaker###SVP, Head of Hypoimmune Platform###Sana Biotechnology###Speaker: – Sana Biotechnology
### she/her/hers1:25 PM – 1:40 PM PT
Type-2 Functionality in Sustaining CAR T Cell Longevity Linked to 8-year Leukemia RemissionLocation: Salon 7Presenting Author: – Yale University
Oral
Zhiliang Bai, PhD – Yale University ### 2288181###Presenting Author###Postdoc Associate###Yale University###Presenting Author: – Yale University
### 1:40 PM – 2:05 PM PT
TCR Engineered Tregs for Autoimmune DiseasesLocation: Salon 7Speaker: – Abata Therapeutics
Devan Moodley, PhD (he/him/his) – Abata Therapeutics ### 2203667###Speaker###Senior Director###Abata Therapeutics###Speaker: – Abata Therapeutics
### he/him/his2:05 PM – 2:20 PM PT
TCR Avidity Influences Signaling and Function of Engineered TregLocation: Salon 7Presenting Author: – Benaroya Research Institute
Oral
Soo Jung Yang, Ph.D. – Benaroya Research Institute ### 987461###Presenting Author######Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 2:20 PM – 2:45 PM PT
Engineering Regulatory T Cells for ToleranceLocation: Salon 7Speaker: – University of British Columbia
Megan K. Levings, PhD (she/her/hers) – University of British Columbia ### 365464###Speaker###Professor###University of British Columbia###Speaker: – University of British Columbia
### she/her/hers1:00 PM – 2:45 PM PT
Host Defense and Vaccinology
1:00 PM – 2:45 PM PT
Host Defense and VaccinologyLocation: Salon 8
Galit Alter, PhD (she/her/hers) – Moderna ### 2203648###Chair###Vice President, Immunology Research###Moderna###Chair: – Moderna
### she/her/hers1:00 PM – 1:25 PM PT
Systems Biological Analysis of the Mechanisms and Predictors of the Durability of Vaccine ResponsesLocation: Salon 8Speaker: – Stanford University
Bali Pulendran, PhD – Stanford University ### 1196163###Speaker###Professor###Stanford University###Speaker: – Stanford University
### 1:25 PM – 1:40 PM PT
SARS-CoV-2 Vaccination Provides Boosted Mucosal Protection in Previously Infected Young ChildrenLocation: Salon 8Presenting Author: – Boston Children's Hospital
Oral
Ying Tang, Ph.D. – Boston Children's Hospital ### 1139949###Presenting Author###Research Fellow###Boston Children's Hospital###Presenting Author: – Boston Children's Hospital
### 1:40 PM – 2:05 PM PT
Human Antibody Response to Human Antibody Response to SARS-CoV-1 and SARS-CoV-2Location: Salon 8Speaker: – Tsinghua University
Linqi Zhang, PhD (he/him/his) – Tsinghua University ### 2203676###Speaker###Professor###Tsinghua University###Speaker: – Tsinghua University
### he/him/his2:05 PM – 2:20 PM PT
Sequential Phases of Follicular Helper T Cell Development and Their Impact on Humoral Immune Responses to VaccinationLocation: Salon 8Presenting Author: – Brigham and Women's Hospital
Oral
Manuel A. Podestà, MD – Brigham and Women's Hospital ### 2288174###Presenting Author###Postdoctoral Research Fellow###Brigham and Women's Hospital###Presenting Author: – Brigham and Women's Hospital
### 2:20 PM – 2:45 PM PT
Dissecting Humoral Vaccine Correlates of Protection Across Respiratory PathogensLocation: Salon 8
Galit Alter, PhD (she/her/hers) – Moderna ### 2203648###Speaker###Vice President, Immunology Research###Moderna###Speaker: – Moderna
### she/her/hers1:00 PM – 2:45 PM PT
Organoid Modeling & TherapeuticsChair: – Charité - Universitätsmedizin Berlin
1:00 PM – 2:45 PM PT
Organoid Modeling & TherapeuticsLocation: Salons 3-6Chair: – Charité - Universitätsmedizin Berlin
Dimitrios L. Wagner, MD, PhD – Charité - Universitätsmedizin Berlin ### 740535###Chair###Research Associate###Charité - Universitätsmedizin Berlin###Chair: – Charité - Universitätsmedizin Berlin
### 1:00 PM – 1:25 PM PT
Tonsil Organoids to Investigate Human Adaptive ImmunityLocation: Salons 3-6Speaker: – University of California Irvine
Lisa Wagar, PhD (she/her/hers) – University of California Irvine ### 2203673###Speaker###Assistant Professor###University of California Irvine###Speaker: – University of California Irvine
### she/her/hers1:25 PM – 1:40 PM PT
Tissue-specific Sex Differences in Pediatric and Adult Immune Cell Composition and FunctionLocation: Salons 3-6Presenting Author: – University of California Irvine
Oral
Mahina Tabassum Mitul, MSc. – University of California Irvine ### 2288180###Presenting Author###Graduate Student Researcher###University of California Irvine###Presenting Author: – University of California Irvine
### 1:40 PM – 2:05 PM PT
Combinatory Differentiation of Human Induced Pluripotent Stem Cells Generates Thymic Epithelium That Supports Thymic Crosstalk and Directs Dendritic- and CD4/CD8 T Cell Full DevelopmentLocation: Salons 3-6Speaker: – Nantes Université / INSERM / CR2TI
Matthieu Giraud, PhD (he/him/his) – Nantes Université / INSERM / CR2TI ### 2203658###Speaker###Group leader, senior researcher###Nantes Université / INSERM / CR2TI###Speaker: – Nantes Université / INSERM / CR2TI
### he/him/his2:05 PM – 2:20 PM PT
Patient-derived Lung Cancer Organoids as 3d-testing Platform for Advanced Personalized TherapiesLocation: Salons 3-6Presenting Author: – Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT)
Oral
Martí Farrera-Sal, PhD – Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT) ### 2288173###Presenting Author######Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT)###Presenting Author: – Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, BIH Center for Regenerative Therapies (BCRT)
### 2:20 PM – 2:45 PM PT
Exploiting Artificial Thymic Organoids for the Modeling of Human FOXP3+ Regulatory T Cell DevelopmentLocation: Salons 3-6Speaker: – McGill University
Ciriaco Piccirillo, PhD (he/him/his) – McGill University ### 738280###Speaker###Principal Investigator, Senior Scientist and Director###McGill University###Speaker: – McGill University
### he/him/his2:45 PM – 3:15 PM PT
Coffee Break
2:45 PM – 3:15 PM PT
Coffee Break
Location: Salon 9
3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 2
3:15 PM – 5:15 PM PT
Flow Cytometry Course: Day 2Location: Salons 10/11Chair: – Stanford University
Speaker:
Speaker:
Speaker:
Holden T. Maecker, PhD – Stanford University ### 387249###Chair###Professor (Research)###Stanford University###Chair: – Stanford University
### @@@ Karan R. Kathuria ### 2041752###Speaker#########Speaker:
### @@@ Haley Pugsley ### 2336849###Speaker#########Speaker:
### @@@ Andy Wu ### 2339729###Speaker#########Speaker:
### 3:15 PM – 5:15 PM PT
Immune MechanismsChair: – University of Florida
3:15 PM – 5:15 PM PT
Immune MechanismsLocation: Salon 8Chair: – University of Florida
Todd Brusko, MD – University of Florida ### 2310147###Chair######University of Florida###Chair: – University of Florida
### 3:15 PM – 3:30 PM PT
Induction of Tolerogenic Dendritic Cell Phenotype Through Natural Killer CellsLocation: Salon 8Presenting Author: – Abbvie
Basic Science of Immunology - Innate Immunity
Ammar J. Alsheikh, MD, PhD – Abbvie ### 2300060###Presenting Author###Senior Scientist###Abbvie###Presenting Author: – Abbvie
### 3:30 PM – 3:45 PM PT
Regulation and Dysregulation of Immune Responses by Human Skin Dendritic Cell SubsetLocation: Salon 8Presenting Author: – Washington University School in St. Louis
Basic Science of Immunology - Innate Immunity
Eynav Klechevsky, PhD – Washington University School in St. Louis ### 1609032###Presenting Author###Assistant professor###Washington University School in St. Louis###Presenting Author: – Washington University School in St. Louis
### 3:45 PM – 4:00 PM PT
The Role of Recirculating Regulatory T Cells in Thymic RegenerationLocation: Salon 8Presenting Author: – Memorial Sloan Kettering Cancer Center
Stem Cell and Organ Transplantation
Andri Leo Lemarquis, MD, PhD – Memorial Sloan Kettering Cancer Center ### 2300059###Presenting Author###Postdoc###Memorial Sloan Kettering Cancer Center###Presenting Author: – Memorial Sloan Kettering Cancer Center
### 4:00 PM – 4:15 PM PT
Single-cell Transcriptomes Reveal Unique CD8 T Cell Atlas Induced by Cytomegalovirus Viremia in Kidney Transplant RecipientsLocation: Salon 8Presenting Author: – University of California, Los Angeles
Systems Immunology
Yumeng (Angela) Sun, B.S. – University of California, Los Angeles ### 1996226###Presenting Author###Graduate Student###University of California, Los Angeles###Presenting Author: – University of California, Los Angeles
### 4:15 PM – 4:30 PM PT
Altered Intestinal Barrier and Immunoregulatory Gut-derived Metabolites Contribute to Acute Rejection in Renal TransplantationLocation: Salon 8Presenting Author: – University College London
Stem Cell and Organ Transplantation
Fernando Yuen Chang, MBCHB – University College London ### 2300061###Presenting Author###PhD Student###University College London###Presenting Author: – University College London
### 4:30 PM – 4:45 PM PT
Unraveling the Mechanistic Regulation of IL-2 Signaling in T Cells and DiseasesLocation: Salon 8Presenting Author: – National Institutes of Health
Basic Science of Immunology - Adaptive Immunity
Suyasha Roy, PhD – National Institutes of Health ### 2300062###Presenting Author###Post-Doctoral Fellow###National Institutes of Health###Presenting Author: – National Institutes of Health
### 4:45 PM – 5:00 PM PT
Helios Regulates CD8 T Cell Activation in Response to TCR AffinityLocation: Salon 8Presenting Author: – Universidad Nacional Autonoma de Mexico
Basic Science of Immunology - Adaptive Immunity
Gerardo Suárez-Rojas – Universidad Nacional Autonoma de Mexico ### 2039553###Presenting Author###PhD Student###Universidad Nacional Autonoma de Mexico###Presenting Author: – Universidad Nacional Autonoma de Mexico
### 5:00 PM – 5:15 PM PT
Modeling COVID-19 in a Humanized Mouse with Functional Human NeutrophilsPresenting Author: – Yale University
Infectious Diseases
Esen Sefik, PhD – Yale University ### 2304214###Presenting Author###Associate Research Scientist###Yale University###Presenting Author: – Yale University
### 3:15 PM – 5:15 PM PT
Immunoengineering and Therapeutics
3:15 PM – 5:15 PM PT
Immunoengineering and TherapeuticsLocation: Salon 7
Jordan Pober, MD, PhD – Yale University ### 399529###Chair######Yale University###Chair: – Yale University
### 3:15 PM – 3:30 PM PT
Tolerogenic IL-2 Containing Nanoparticles Induce CD4 and CD8 Regulatory T Cells and TGF-β Producing Regulatory NK Cells That Provide Essential Support for the Tregs Which Suppress Immune-mediated DisordersLocation: Salon 7Presenting Author: – General Nanotherapeutics, LLC
Immuno-engineering and Cellular Therapies
David A. Horwitz, MD – General Nanotherapeutics, LLC ### 1310167###Presenting Author###Founder###General Nanotherapeutics, LLC###Presenting Author: – General Nanotherapeutics, LLC
### 3:30 PM – 3:45 PM PT
Rosnilimab, a PD-1 Agonist Antibody That Binds to a Membrane Proximal Epitope Leading to Optimized PD-1 Agonistic SignalingLocation: Salon 7Presenting Author: – AnaptysBio
Basic Science of Immunology - Adaptive Immunity
Stephen Parmley, PhD – AnaptysBio ### 751445###Presenting Author######AnaptysBio###Presenting Author: – AnaptysBio
### 3:45 PM – 4:00 PM PT
IL-10 Producing Tolerogenic Dendritic Cells Modulate B Cell Responses in vitro and in vivoLocation: Salon 7Presenting Author: – San Raffaele Telethon institute for Gene Therapy
Immuno-engineering and Cellular Therapies
Silvia Gregori, PhD – San Raffaele Telethon institute for Gene Therapy ### 365554###Presenting Author###Dr###San Raffaele Telethon institute for Gene Therapy###Presenting Author: – San Raffaele Telethon institute for Gene Therapy
### 4:00 PM – 4:15 PM PT
Precision Therapy for Lupus: Targeting Follicular Helper T Cells Using Chimeric Antigen Receptor Natural Killer CellsLocation: Salon 7Presenting Author: – Cincinnati Children's Hospital
Immuno-engineering and Cellular Therapies
Nora Lakes (they/them/theirs) – Cincinnati Children's Hospital ### 1945914###Presenting Author###MD-PhD student###Cincinnati Children's Hospital###Presenting Author: – Cincinnati Children's Hospital
### they/them/theirs4:15 PM – 4:30 PM PT
T-cell Receptor Precision Editing of Regulatory T-cells for Celiac DiseaseLocation: Salon 7Presenting Author: – Lausanne University Hospital and University of Lausanne
Immuno-engineering and Cellular Therapies
Raphael Porret – Lausanne University Hospital and University of Lausanne ### 1608581###Presenting Author###MD-PhD student###Lausanne University Hospital and University of Lausanne###Presenting Author: – Lausanne University Hospital and University of Lausanne
### 4:30 PM – 4:45 PM PT
Regeneration of a Sustained Antiviral Response in Transplant Recipients by Tacrolimus Resistant Antiviral T-cell ProductsLocation: Salon 7Presenting Author: – Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin
Immuno-engineering and Cellular Therapies
Niklas Wiese – Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin ### 2041855###Presenting Author######Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin###Presenting Author: – Berlin Center for Advanced Therapies, Charité-Universitätsmedizin Berlin
### 4:45 PM – 5:00 PM PT
Expanding Our Understanding of PDC-E2 T Cell Responses in PBC and Their Application for Eng Treg TherapyLocation: Salon 7Presenting Author: – Benaroya Research Institute
Autoimmune Diseases
Ritika Tewari, PhD – Benaroya Research Institute ### 2300054###Presenting Author###Staff Scientist###Benaroya Research Institute###Presenting Author: – Benaroya Research Institute
### 5:00 PM – 5:15 PM PT
Gene-edited Allogeneic Regulatory T Cells as 'Off-the-shelf' Immunomodulatory Therapy for TransplantationLocation: Salon 7Presenting Author: – Charité - Universitätsmedizin Berlin
Immuno-engineering and Cellular Therapies
Dimitrios L. Wagner, MD, PhD – Charité - Universitätsmedizin Berlin ### 740535###Presenting Author###Research Associate###Charité - Universitätsmedizin Berlin###Presenting Author: – Charité - Universitätsmedizin Berlin
### 3:15 PM – 5:15 PM PT
Immuno-oncologyChair: – Mayo Clinic
Co-Chair: – Mayo Clinic
3:15 PM – 5:15 PM PT
Immuno-oncologyLocation: Salons 3-6Chair: – Mayo Clinic
Co-Chair: – Mayo Clinic
Khashayarsha Khazaie, PhD, D.Sc. – Mayo Clinic ### 2041929###Chair######Mayo Clinic###Chair: – Mayo Clinic
### @@@ Amir A. Sadighi Akha, M.D., Ph.D. – Mayo Clinic ### 985575###Co-Chair######Mayo Clinic###Co-Chair: – Mayo Clinic
### 3:15 PM – 3:30 PM PT
Spatially Exploring RNA Biology in Archival Formalin-fixed Paraffin-embedded TissuesLocation: Salons 3-6Presenting Author: – Yale University
Systems Immunology
Zhiliang Bai, PhD – Yale University ### 2288181###Presenting Author###Postdoc Associate###Yale University###Presenting Author: – Yale University
### 3:30 PM – 3:45 PM PT
Peripheral Blood as a Source to Identify Candidate Neoantigens and Reactive TCRsLocation: Salons 3-6Presenter: – Vall d'Hebron Institute of Oncology
Co-Author: – Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona
Immuno-oncology
Andrea Garcia-Garijo – Vall d'Hebron Institute of Oncology ### 1945874###Presenter###PhD student###Vall d'Hebron Institute of Oncology###Presenter: – Vall d'Hebron Institute of Oncology
### @@@ Ricardo Pujol Borrell, MD, PhD – Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona ### 366553### Co-Author###Emeritus Professor###Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona### Co-Author: – Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona
### 3:45 PM – 4:00 PM PT
Helios Limits CD8 T Cell Antitumor CapacityLocation: Salons 3-6Presenting Author: – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Immuno-oncology
Rosa M. Rubio – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran ### 2300064###Presenting Author######Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran###Presenting Author: – Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
### 4:00 PM – 4:15 PM PT
Secondary Inhibitory Signals on Human Kidney Microvascular Endothelium Confer Peripheral T Cell Tolerance: Insight from Checkpoint Inhibitor ToxicityLocation: Salons 3-6Presenting Author: – University of Washington
Immuno-oncology
Kimberly Muczynski, MD, PhD – University of Washington ### 1945923###Presenting Author###Associate Professor###University of Washington###Presenting Author: – University of Washington
### 4:15 PM – 4:30 PM PT
CAR T Cell Therapy Targeting CD84 Alone or in Combination with CD19 for the Treatment of B Cell MalignanciesLocation: Salons 3-6Presenting Author: – Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)
Immuno-engineering and Cellular Therapies
Ane Altuna Mongelos – Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) ### 2300156###Presenting Author######Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)###Presenting Author: – Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)
### 4:30 PM – 4:45 PM PT
HIV-associated Lung Cancer Exhibits an Immunoregulatory Tumor MicroenvironmentLocation: Salons 3-6Presenting Author: – Yale University
Immuno-oncology
Brinda Emu, MD – Yale University ### 1319794###Presenting Author######Yale University###Presenting Author: – Yale University
### 4:45 PM – 5:00 PM PT
Exclusion of PD-1 from the Immune Synapse: A Novel Strategy to Modulate T Cell FunctionLocation: Salons 3-6Presenter: – Columbia University
Immuno-oncology
Matthieu J. Paiola, PhD – Columbia University ### 2304241###Presenter###Associate Research Scientist###Columbia University###Presenter: – Columbia University
### 5:00 PM – 5:15 PM PT
TMEM176B Is a Druggable Intrinsic Driver of Protumoral Th17 LymphocytesLocation: Salons 3-6Presenting Author: – Institut Pasteur de Montevideo
Immuno-oncology
Marcelo Hill, MD, PhD – Institut Pasteur de Montevideo ### 1319274###Presenting Author######Institut Pasteur de Montevideo###Presenting Author: – Institut Pasteur de Montevideo
### 5:30 PM – 5:45 PM PT
State of FOCIS
5:30 PM – 5:45 PM PT
State of FOCIS AddressLocation: Salon 8Speaker: – Columbia University
Megan Sykes, MD (she/her/hers) – Columbia University ### 366755###Speaker###Michael J. Friedlander Professor of Medicine and Professor of Microbiology & Immunology and Surgical Sciences (in Surgery), Columbia UniversityDirector, Columbia Center for Translational Immunology, Columbia University College of Physicians and SurgeonsDirector of Research, Transplant Initiative, Director, Bone Marrow Transplantation Research, Division of Hematology/OncologyColumbia University Medical Center###Columbia University###Speaker: – Columbia University
### she/her/hers5:45 PM – 6:30 PM PT
Keynote Address
5:45 PM – 6:30 PM PT
Keynote Address: Decoding the Missing Link: From Loss of Tolerance to Tissue DestructionLocation: Salon 8Speaker: – University of Chicago
Chair: – Columbia University
Bana Jabri, MD, PhD – University of Chicago ### 906789###Speaker######University of Chicago###Speaker: – University of Chicago
### @@@ Joshua Milner, MD – Columbia University ### 1611209###Chair###Principal Investigator###Columbia University###Chair: – Columbia University
### 6:30 PM – 7:45 PM PT
Exhibit and Poster Reception
6:30 PM – 7:45 PM PT
Exhibit and Poster ReceptionLocation: Salon 9
- Friday, June 21, 2024
7:00 AM – 3:45 PM PT
Registration Desk Open
7:00 AM – 3:45 PM PT
Registration Desk Open
Location: Registration Desk
8:00 AM – 9:30 AM PT
Somatic Mosaicism, Clonal Populations and Immune DisordersChair: – Translational Immunology Institute, SingHealth
8:00 AM – 9:30 AM PT
Somatic Mosaicism, Clonal Populations and Immune DisordersLocation: Salon 8Chair: – Translational Immunology Institute, SingHealth
Salvatore Albani, MD, PhD – Translational Immunology Institute, SingHealth ### 365688###Chair###Director###Translational Immunology Institute, SingHealth###Chair: – Translational Immunology Institute, SingHealth
### 8:00 AM – 8:30 AM PT
Somatic Mosaicism in Genetic Diseases of the Immune SystemLocation: Salon 8Speaker: – Washington University in St. Louis
Megan A. Cooper, MD, PhD (she/her/hers) – Washington University in St. Louis ### 651470###Speaker###Professor###Washington University in St. Louis###Speaker: – Washington University in St. Louis
### she/her/hers8:30 AM – 9:00 AM PT
From Mosaics to Clones: Aligning Terminology in Genetic VariabilityLocation: Salon 8Speaker: – Weill Cornell Medicine
Monica L. Guzman, PhD (she/her/hers) – Weill Cornell Medicine ### 751352###Speaker###Associate Professor of Pharmacology in Medicine###Weill Cornell Medicine###Speaker: – Weill Cornell Medicine
### she/her/hers9:00 AM – 9:30 AM PT
Mechanisms That Contribute Towards Female-biased Autoimmunity: X-chromosome InactivationLocation: Salon 8Speaker: – University of Pennsylvannia
Montserrat Anguera, PhD (she/her/hers) – University of Pennsylvannia ### 2203650###Speaker###Associate Professor###University of Pennsylvannia###Speaker: – University of Pennsylvannia
### she/her/hers9:30 AM – 10:00 AM PT
Coffee Break
9:30 AM – 10:00 AM PT
Coffee Break
Location: Yerba Buena Grand Assembly
10:00 AM – 11:30 AM PT
Mechanisms & Treatment of AutoimmunityChair: – Washington University in St. Louis
10:00 AM – 11:30 AM PT
Mechanisms & Treatment of AutoimmunityLocation: Salon 8Chair: – Washington University in St. Louis
Michael M. Paley, MD, PhD – Washington University in St. Louis ### 2040065###Chair######Washington University in St. Louis###Chair: – Washington University in St. Louis
### 10:00 AM – 10:30 AM PT
Enhancing Treg Therapy Through Cell EngineeringLocation: Salon 8Speaker: – University of California, San Francisco
Qizhi Tang, PhD (she/her/hers) – University of California, San Francisco ### 365695###Speaker###Professor###University of California, San Francisco###Speaker: – University of California, San Francisco
### she/her/hers10:30 AM – 11:00 AM PT
APS-1/APECED: Mechanisms & Treatment of AutoimmunityLocation: Salon 8Speaker: – National Institute of Allergy and Infectious Diseases
Michail S. Lionakis, MD, ScD (he/him/his) – National Institute of Allergy and Infectious Diseases ### 1541312###Speaker###Chief, Fungal Pathogenesis Section, Laboratory of Clinical Immunology & Microbiology###National Institute of Allergy and Infectious Diseases###Speaker: – National Institute of Allergy and Infectious Diseases
### he/him/his11:00 AM – 11:30 AM PT
RNA Origin of Sex Biased ImmunityLocation: Salon 8Speaker: – Stanford University
Howard Chang, MD, PhD – Stanford University ### 389563###Speaker###Director, Center for Personal Dynamic RegulomesVirginia & D.K. Ludwig Professor of Cancer GenomicsProfessor of Dermatology and of GeneticsStanford University School of MedicineInvestigator, Howard Hughes Medical Institute###Stanford University###Speaker: – Stanford University
### 11:45 AM – 12:30 PM PT
Keynote Session
11:45 AM – 12:30 PM PT
Keynote Address: Cell, Tissue and Perturbation Atlases as Roadmaps in CancerLocation: Salon 8Speaker: – Genentech
Chair: – Washington University in St. Louis
Aviv Regev, PhD – Genentech ### 2203670###Speaker###Executive Vice President, Research and Early Development###Genentech###Speaker: – Genentech
### @@@ Megan A. Cooper, MD, PhD (she/her/hers) – Washington University in St. Louis ### 651470###Chair###Professor###Washington University in St. Louis###Chair: – Washington University in St. Louis
### she/her/hers12:45 PM – 2:00 PM PT
Industry and Partner Lunch Programs
12:45 PM – 2:00 PM PT
Industry and Partner Lunch Programs
12:45 PM – 2:00 PM PT
Partner Program: Journal of Experimental Medicine – Meet the EditorLocation: Salons 1/2Speaker: – Journal of Experimental Medicine (JEM)
Shachi Bhatt, PhD – Journal of Experimental Medicine (JEM) ### 1678429###Speaker###Executive Editor###Journal of Experimental Medicine (JEM)###Speaker: – Journal of Experimental Medicine (JEM)
### 12:45 PM – 2:00 PM PT
Partner Program: NIAID Research Support: The Life of a Grant from Concept to Award Location: Nob Hill A-DSpeaker: – Division of Allergy, Immunology, and Transplantation, NIAID/NIH
Speaker: – Division of Allergy, Immunology, and Transplantation, NIAID/NIH
Speaker: – Scientific Review Program, NIAID/NIH
Stacy E. Ferguson, PhD – Division of Allergy, Immunology, and Transplantation, NIAID/NIH ### 2364829###Speaker###Section Chief - Autoimmunity and Primary Immunodeficiency Diseases Section Autoimmunity and Mucosal Immunology Branch###Division of Allergy, Immunology, and Transplantation, NIAID/NIH###Speaker: – Division of Allergy, Immunology, and Transplantation, NIAID/NIH
### @@@ Jeffrey Rice, PhD – Division of Allergy, Immunology, and Transplantation, NIAID/NIH ### 508927###Speaker###Program Officer###Division of Allergy, Immunology, and Transplantation, NIAID/NIH###Speaker: – Division of Allergy, Immunology, and Transplantation, NIAID/NIH
### @@@ Poonam Tewary, PhD – Scientific Review Program, NIAID/NIH ### 2364830###Speaker###Scientific Review Officer###Scientific Review Program, NIAID/NIH###Speaker: – Scientific Review Program, NIAID/NIH
### 2:00 PM – 3:45 PM PT
Behavioral Immunology and NeuroimmunologyChair: – Institute of Primate Research
2:00 PM – 3:45 PM PT
Behavioral Immunology and NeuroimmunologyLocation: Salon 8Chair: – Institute of Primate Research
Lucy Ochola, PhD – Institute of Primate Research ### 2380254###Chair######Institute of Primate Research###Chair: – Institute of Primate Research
### 2:00 PM – 2:25 PM PT
Sickness Behaviors of Type 2 ImmunityLocation: Salon 8Speaker: – Arizona State University
Esther Borges Florsheim, PhD – Arizona State University ### 2203651###Speaker###Assistant Professor###Arizona State University###Speaker: – Arizona State University
### 2:25 PM – 2:40 PM PT
Longitudinal Analysis of Immune Cell Changes in FUS-ALS Patients Treated with a FUS Antisense OligonucleotideLocation: Salon 8Presenting Author: – Columbia University
Oral
Olivia M. Rifai, PhD – Columbia University ### 2288178###Presenting Author###Postdoctoral Fellow###Columbia University###Presenting Author: – Columbia University
### 2:40 PM – 3:05 PM PT
Unique Aspects of IFN-γ/STAT1 Signaling in NeuronsLocation: Salon 8Speaker: – Duke University, Marcus Center for Cellular Cures
Anthony Filiano, PhD – Duke University, Marcus Center for Cellular Cures ### 2203657###Speaker###Assistant Professor###Duke University, Marcus Center for Cellular Cures###Speaker: – Duke University, Marcus Center for Cellular Cures
### 3:05 PM – 3:20 PM PT
Greater Composite Confirmed Disability Progression in Non-Hispanic Black and Hispanic or Latino Individuals with Relapsing Multiple Sclerosis: Analysis of Self-reported Identity and Genetic Ancestry in the OPERA I and II TrialsLocation: Salon 8Presenting Author: – Genentech
Oral
Xiaoming Jia, MD, MEng – Genentech ### 2288179###Presenting Author###Group Medical Director###Genentech###Presenting Author: – Genentech
### 3:20 PM – 3:45 PM PT
Sensory Neuron Regulation of Host Defense and ImmunityLocation: Salon 8Speaker: – Harvard University
Isaac Chiu, PhD – Harvard University ### 2203652###Speaker###Associate Professor###Harvard University###Speaker: – Harvard University
### 2:00 PM – 3:45 PM PT
Immuno-oncologyChair: – Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona
2:00 PM – 3:45 PM PT
Immuno-oncologyLocation: Salon 7Chair: – Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona
Ricardo Pujol Borrell, MD, PhD – Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona ### 366553###Chair###Emeritus Professor###Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona###Chair: – Vall d'Hebron Institute of Oncology, Universitat Autonoma de Barcelona
### 2:00 PM – 2:25 PM PT
Reprogramming the Tumor-immune Microenvironment by Targeting the Galectin-glycan AxisLocation: Salon 7Speaker: – Instituto de Biología y Medicina Experimental
Gabriel Rabinovich, PhD (he/him/his) – Instituto de Biología y Medicina Experimental ### 2203669###Speaker###Head Laboratory Glycomedicine, IBYME and Professor of Immunology, University of Buenos Aires###Instituto de Biología y Medicina Experimental###Speaker: – Instituto de Biología y Medicina Experimental
### he/him/his2:25 PM – 2:40 PM PT
Pre-existing Skin-resident CD8 and γδ T Cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy EfficacyLocation: Salon 7Presenting Author: – Northwestern University
Oral
Zachary Zale Reinstein – Northwestern University ### 2288171###Presenting Author######Northwestern University###Presenting Author: – Northwestern University
### 2:40 PM – 3:05 PM PT
GD2-CAR T Cell Therapy for Diffuse Midline GliomasLocation: Salon 7Speaker: – Stanford University
Michelle Monje, MD, PhD (she/her/hers) – Stanford University ### 2219549###Speaker###Professor, Neurology & Neurological Sciences ###Stanford University###Speaker: – Stanford University
### she/her/hers3:05 PM – 3:20 PM PT
Aire-expressing Tumor-associated Macrophages Promote Cancer Immune EvasionLocation: Salon 7Presenting Author: – University of California, San Francisco
Oral
Matthew Arvedson – University of California, San Francisco ### 2288172###Presenting Author###Graduate Student###University of California, San Francisco###Presenting Author: – University of California, San Francisco
### 3:20 PM – 3:45 PM PT
Adipocyte-secreted interleukin-9 Promotes B Cell Acute Lymphoblastic Leukemia ProgressionLocation: Salon 7Speaker: – University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus
Curtis J. Henry, PhD (he/him/his) – University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus ### 2203660###Speaker###Deputy Associate Director of DEIA/Associate Professor of Immunology and Microbiology###University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus###Speaker: – University of Colorado Cancer Center/University of Colorado Anschutz Medical Campus
### he/him/his2:00 PM – 3:45 PM PT
Metabolic Regulation of InflammationChair: – Stanford University
2:00 PM – 3:45 PM PT
Metabolic Regulation of InflammationLocation: Salons 3-6Chair: – Stanford University
Jonathan S. Maltzman, MD, PhD, FAST – Stanford University ### 399526###Chair###Associate Professor###Stanford University###Chair: – Stanford University
### 2:00 PM – 2:25 PM PT
An Immunometabolic Circuit Triggered by Dietary ChitinLocation: Salons 3-6Speaker: – Washington University in St. Louis
Steven Van Dyken, PhD (he/him/his) – Washington University in St. Louis ### 2203672###Speaker###Assistant Professor###Washington University in St. Louis###Speaker: – Washington University in St. Louis
### he/him/his2:25 PM – 2:40 PM PT
Human Tolerogenic Dendritic Cells Used in Clinic Regulate CD8+ T Cell PopulationLocation: Salons 3-6Presenting Author: – CR2TI UMR1064
Oral
Maaike Suuring, PhD – CR2TI UMR1064 ### 2288175###Presenting Author######CR2TI UMR1064###Presenting Author: – CR2TI UMR1064
### 2:40 PM – 3:05 PM PT
Integrating Systems Immunology with Metabolism and CancerLocation: Salons 3-6Speaker: – St. Jude Children's Research Hospital
Hongbo Chi, PhD – St. Jude Children's Research Hospital ### 651468###Speaker###Member###St. Jude Children's Research Hospital###Speaker: – St. Jude Children's Research Hospital
### 3:05 PM – 3:20 PM PT
Skeletal Muscle DUPD1 Links Gut Inflammation with Obesity-associated Metabolic DiseasesLocation: Salons 3-6Presenting Author: – University of Toronto
Oral
Alberto Martin, PhD (he/him/his) – University of Toronto ### 985585###Presenting Author###Professor###University of Toronto###Presenting Author: – University of Toronto
### he/him/his3:20 PM – 3:45 PM PT
Immunometabolism at the Crossroads Between Inflammation and AgingLocation: Salons 3-6Speaker: – Centro de Biologia Molecular Severo Ochoa
Maria Mittelbrunn, PhD – Centro de Biologia Molecular Severo Ochoa ### 2203665###Speaker###Head of Immunometabolism and Inflamamtion Lab###Centro de Biologia Molecular Severo Ochoa###Speaker: – Centro de Biologia Molecular Severo Ochoa
###
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