Session: Somatic Mosaicism, Clonal Populations and Immune Disorders

Mechanisms That Contribute Towards Female-biased Autoimmunity: X-chromosome Inactivation

Friday, June 21, 2024

9:00 AM – 9:30 AM PT

Location: Salon 8

Speaker(s)

Montserrat Anguera, PhD

Associate Professor
University of Pennsylvannia
Philadelphia, Pennsylvania, United States

Disclosure(s):

Montserrat Anguera, PhD: No financial relationships to disclose

to recognize some of the prominent epigenetic features of the inactive X chromosome that are altered in autoimmune diseases with a female bias
to understand that X-chromosome Inactivation contributes to sex-biased expression in lymphocytes
to describe some female-biased autoimmune disorders where X-Chromosome Inactivation is altered